Related Experiment Videos
[Granulocyte-macrophage colony-stimulating factor in the treatment of secondary bone marrow suppression in patients
A Avilés1, J C Díaz-Maqueo, A Talavera
1Departamento de Hematología, Centro Médico Nacional, IMSS, México, D.F.
Archivos De Investigacion Medica
|April 1, 1990
Abstract:
Four patients with severe myelosuppression secondary to chemotherapy for advanced malignant lymphoma were treated with human granulocyte macrophage colony-stimulating factor (GM-CSF) at dose of 10 micrograms/kg/day. The number of absolute granulocytes increase in all patients in the first 3 days after the treatment was begun. Normal values were observed after 5 days on treatment. No toxicities resulted from the treatment. The results demonstrate the utility of GC-CSF in restoring normal granulocytes counts in patients undergoing intensive chemotherapy.