Related Experiment Videos
Multiple vascular eccrine spiradenomas: a case report and published work review of multiple eccrine spiradenomas
Aki Yoshida1, Kazuhiro Takahashi, Fumihiko Maeda
1Department of Dermatology, Iwate Medical University School of Medicine, Morioka, Japan. akiyoshida0629@yahoo.co.jp
The Journal of Dermatology
|November 3, 2010
Summary
Multiple vascular eccrine spiradenomas (VES), a rare variant of eccrine spiradenoma, presented unusually in a 55-year-old woman. This case highlights the rarity of multifocal VES and contributes to understanding ES classification.
Area of Science:
- Dermatology
- Oncology
- Pathology
Background:
- Eccrine spiradenoma (ES) typically presents as a solitary nodule.
- Rare presentations include multifocal or multiple tumors in linear, zosteriform, or nevoid patterns.
Observation:
- A 55-year-old woman presented with a 48-year history of multiple vascular eccrine spiradenomas (VES) on the left submandibular region and neck.
- The five tumors were skin-colored to pinkish-purple, measuring 1.5-2.5 cm.
- Histology revealed characteristic ES cell types and prominent dilated vascular spaces within the stroma.
Findings:
- Contrast-enhanced CT demonstrated central enhancement in the tumors.
- A literature review identified 35 cases of multiple ES, with multiple VES being exceptionally rare.
- The study summarizes features of previously reported multiple ES cases.
Implications:
- This case underscores the extreme rarity of multiple VES.
- Further discussion on the clinical and histological classification of ES is warranted.
- Understanding rare presentations of ES is crucial for accurate diagnosis and management.
Related Concept Videos
01:30Skin Cancer
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
01:19Clinical Applications of Epidermal Stem Cells
Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own EpiSCs...
02:23Abnormal Proliferation
Under normal conditions, most adult cells remain in a non-proliferative state unless stimulated by internal or external factors to replace lost cells. Abnormal cell proliferation is a condition in which the cell's growth exceeds and is uncoordinated with normal cells. In such situations, cell division persists in the same excessive manner even after cessation of the stimuli, leading to persistent tumors. The tumor arises from the damaged cells that replicate to pass the damage to the daughter...