Related Experiment Video
Updated: Jun 7, 2026

Chronic Salmonella Infection Induced Intestinal Fibrosis
Published on: September 22, 2019
[Intestinal tuberculosis as a differential diagnosis of inflammatory bowel disease]
Anders Lødrup1, Susanne Eiholm, Christian Meyer
1Køge Sygehus, Medicinsk Afdeling, Denmark. loedrup.ab@gmail.com
Abstract:
Intestinal tuberculosis (ITB) is a rare differential diagnosis of inflammatory bowel disease (IBD) in Denmark. In the presented case, a 44-year-old native Danish man was examined for IBD symptoms. Colonoscopy and microscopy of colonic biopsies suggested IBD. The patient was started on steroid therapy, but without effect so tumour necrosis factor alpha therapy was planned. Routine interferon-gamma release assay was normal, but chest X-ray revealed an apical infiltration. New tests on the colonic biopsies using polymerase chain reaction were positive for Mycobacterium tuberculosis and the patient was treated for ITB and pulmonary tuberculosis.
Related Concept Videos
Inflammatory Bowel Disease I: Introduction
Inflammatory Bowel Disease II: Crohn's Disease
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by transmural...
Inflammatory Bowel Disease I: Ulcerative Colitis
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Inflammatory Bowel Disease III: Crohn's Disease
Inflammatory Bowel Disease IV: Clinical Manifestations
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the colonic...