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Hemicrania continua: a second case in which the remitting form evolved from the chronic form
Lisa A Yablon1, Lawrence C Newman
1Headache Institute, Roosevelt Hospital, New York, NY 10019, USA.
Headache
|November 4, 2010
Summary
This case study details a patient whose chronic hemicrania continua transformed into remitting hemicrania continua over 15 years. This documented transition is only the second instance reported in medical literature.
Area of Science:
- Neurology
- Clinical Neuroscience
Background:
- Hemicrania continua is a primary headache disorder characterized by continuous unilateral pain with exacerbations.
- The pathophysiology of hemicrania continua is not fully understood, but it is thought to involve trigeminal nerve activation.
Observation:
- A patient with a 15-year history of chronic hemicrania continua presented with a documented evolution of her headache pattern.
- The headache phenotype shifted from continuous daily pain to episodes of pain separated by pain-free intervals.
Findings:
- This represents the second reported case of chronic hemicrania continua transitioning to remitting hemicrania continua.
- The transition suggests a potential evolution or distinct phases within the spectrum of hemicrania continua.
Implications:
- Understanding this transition may offer new insights into the underlying mechanisms of hemicrania continua.
- Further research is warranted to explore the factors contributing to such phenotypic changes in headache disorders.
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