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[Mitral valve prolapse detected during hemodynamic studies]
J P Dubiel1, T Królikowski, T Brzostek
1I Kliniki Kardiologii Instytutu Kardiologii AM w Krakowie.
Insights
Posterior mitral valve leaflet prolapse is uncommon in routine left ventriculography, affecting 5.9% of patients. It was most common in atrial septal defects and myocardial lesions, suggesting left ventricle size plays a role.
Area of Science:
- Cardiology
- Diagnostic Imaging
Background:
- Posterior mitral valve leaflet prolapse (PMVLp) is a cardiac condition.
- Routine left ventriculography is a common diagnostic procedure.
Purpose of the Study:
- To determine the frequency of PMVLp in patients undergoing routine left ventriculography.
- To investigate potential associations between PMVLp and specific cardiac conditions.
Main Methods:
- Analysis of 1000 consecutive left ventriculograms (right anterior oblique projection).
- Patient cohort: 511 women, 489 men; mean age 46.5 years.
- Exclusion criteria: patients with coronary artery disease.
Main Results:
- PMVLp was diagnosed in 59 patients (5.9%).
- Idiopathic mitral valve prolapse was diagnosed in 10 patients.
- PMVLp was most frequent in atrial septal defect (16.6%), myocardial lesion (12.5%), and post-mitral commissurotomy (8.9%).
Conclusions:
- PMVLp is not a frequent anomaly in routine left ventriculography.
- The higher prevalence in atrial septal defect suggests a role for left ventricle size in PMVLp pathogenesis.
Abstract:
To estimate frequency of the posterior mitral valve leaflet prolapse in routinely performed left ventriculography, 1000 consecutive ventriculograms of the right anterior oblique projection were analyzed. A group of patients consisted of 511 women and 489 men at mean age 46,5 years. Clinical diagnosis of heart lesions, myocardial disease, pulmonary hypertension or arrhythmias were indications for hemodynamic studies. In the investigated group of patients, there were no patients with clinical diagnosis of the coronary artery disease. Prolapse of the posterior mitral valve leaflet was diagnosed in 59 patients. Idiopathic mitral valve prolapse was diagnosed in 10 patients. Prolapse of the posterior mitral valve leaflet was most frequent in atrial septal defect (16.6%), myocardial lesion (12.5%), and after mitral commissurotomy (8.9%). Posterior mitral valve leaflet prolapse is not a frequent anomaly in routinely performed left ventriculography. Relatively often occurrence of the mitral valve prolapse in atrial septal defect and only occasional in the aortic lesions and dilated cardiomyopathy seems to point out at a role of the left ventricle size in pathogenesis of this syndrome.