Percutaneous coronary intervention in the elderly: results from the Thai National Percutaneous Coronary Intervention
Songsak Kiatchoosakun1, Pattarapong Keelapang, Pinij Kaewsuwana
1Division of Cardiology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand. sonkia@kku.ac.th
Insights
Percutaneous coronary intervention (PCI) is safe for elderly patients in Thailand. Advanced age did not predict in-hospital mortality, though elderly patients experienced higher complication rates.
Area of Science:
- Cardiology
- Geriatric Medicine
- Health Outcomes Research
Background:
- Percutaneous coronary intervention (PCI) is a common procedure for coronary artery disease.
- Elderly patients often present with more comorbidities, potentially impacting PCI outcomes.
- Understanding mortality risk factors in this demographic is crucial for clinical decision-making.
Purpose of the Study:
- To assess the outcomes of PCI in elderly patients in Thailand.
- To identify risk factors associated with in-hospital mortality in this population.
Main Methods:
- Retrospective analysis of 4,156 patients undergoing PCI (May 2006 - October 2007).
- Comparison of outcomes between elderly (≥75 years) and non-elderly (<75 years) groups.
- Multivariate analysis to identify predictors of in-hospital mortality.
Main Results:
- Elderly patients had lower PCI success rates (87.5% vs 91.2%) and higher rates of renal failure (3.9% vs 1.8%) and Q-wave myocardial infarction (3.0% vs 1.4%).
- Unadjusted in-hospital mortality was higher in elderly patients (5.3% vs 2.4%).
- Acute coronary syndrome and heart failure were significant predictors of mortality; advanced age was not (OR=1.37, p=0.174).
Conclusions:
- PCI is a safe and effective procedure for elderly patients in Thailand.
- Advanced age itself is not a significant predictor of in-hospital mortality after PCI.
- Focusing on comorbidities like acute coronary syndrome and heart failure is key for risk stratification.
Aims:
The objective of this study was to evaluate the outcomes and identify the risk factors of in-hospital mortality among elderly patients undergoing PCI in Thailand.
Methods And Results:
Included in this study were 4,156 consecutive patients (comprising 639 elderly [age ≥ 75 years] and 3,517 non-elderly [age < 75 years]) undergoing PCI between May 2006 and October 2007. The success rate of PCI was less favourable among elderly compared to the non-elderly patients (91.2% vs. 87.5%; p=0.003). Elderly patients had higher rate of post PCI renal failure (3.9% vs. 1.8%; p=0.001), Q-wave myocardial infarction (3.0 vs. 1.4%, p=0.003), and unadjusted in-hospital mortality (5.3% vs. 2.4%, p ≤ 0.001), compared with non-elderly patients. After adjustment for baseline variables, acute coronary syndrome and heart failure were the two variables most associated with increased mortality (OR=5.95, 95% CI=3.22-11.01), p<0.001 and OR=5.73,95% CI=3.80-8.63), p<0.001, respectively). According to the multivariate analysis, age was not significantly related with increased mortality (OR=1.37, 95% CI=0.87-2.16, p=0.174).
Conclusions:
Our study highlights the safety and effectiveness of PCI in elderly patients since advanced age is not a predictor of in-hospital mortality.
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