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High-Throughput Behavioral Aging and Lifespan Assays Using the Lifespan Machine

High-Throughput Behavioral Aging and Lifespan Assays Using the Lifespan Machine

Published on: January 26, 2024

Ensembl 2011.

Paul Flicek¹, M Ridwan Amode, Daniel Barrell

¹European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK. flicek@ebi.ac.uk

Nucleic Acids Research

|November 4, 2010

Summary

This summary is machine-generated.

The Ensembl project provides high-quality genomic annotation for chordate and eukaryotic species. This resource supports genomic science by integrating gene, variation, and regulatory data for key research organisms.

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Area of Science:

Genomics
Bioinformatics
Comparative Genomics

Background:

The Ensembl project offers integrated genomic annotation for various species.
It provides a consistent infrastructure for accessing and analyzing genomic data.

Purpose of the Study:

To enable genomic science through high-quality, integrated annotation of eukaryotic genomes.
To enhance the presentation and integration of disease-relevant data and cell-type-specific regulatory information.

Main Methods:

Comprehensive, evidence-based gene annotation for all supported species.
Inclusion of variation, comparative, evolutionary, functional, and regulatory annotation for selected genomes.
Advanced resources for key species like human, mouse, rat, and zebrafish.

Main Results:

As of release 59 (August 2010), 56 species are supported, with 5 added in the past year.
Substantial improvements in the presentation and integration of disease data.
Enhanced integration of regulatory state data for different cell types.

Conclusions:

Ensembl provides a robust and evolving platform for genomic research.
The project continuously expands its species coverage and data types.
Improvements focus on disease relevance and cellular regulatory information.