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Published on: September 20, 2024
Corneal morphological changes after myopic excimer laser refractive surgery
Nicola Rosa1, Maria Borrelli, Maddalena De Bernardo
1Centro Grandi Apparecchiature, 2nd University of Naples, Naples, Italy. nicola.rosa@unina2.it
Purpose:
To evaluate the changes in central corneal thickness (CCT) and corneal volume (CV) in eyes that have undergone myopic photorefractive keratectomy (PRK).
Methods:
CCT and CV obtained with an Oculus Pentacam before 1, 3, and 6 months after PRK were analyzed in 84 eyes with a mean preoperative refraction of -4.93 ± 2.23 diopter. The changes were compared with the amount of refractive treatment. The differences were evaluated with the Student t test and the correlations with the Pearson index.
Results:
One month after PRK, CCT and CV mean differences were 73.2 ± 31.5 μm (P < 0.001) and 2.2 ± 1.7 mm (P < 0.001), respectively. Three months after PRK, CCT and CV mean differences were 66.6 ± 26.7 μm (P < 0.001) and 1.4 ± 1.3 mm (P < 0.001), respectively. Six months after PRK, CCT and CV mean differences were 65.3 ± 25.7 μm (P < 0.001) and 1.4 ± 1.3 mm (P < 0.001), respectively. The effective treatment at each follow-up point was correlated with CCT changes (R = 0.62, 0.71, and 0.73, respectively), but not with CV changes (R = 0.04, 0.04, and 0.01, respectively).
Conclusions:
Our findings support the hypothesis that after myopic PRK, when a series of corneal lamellae are severed centrally, the remaining peripheral segments relax. The squeezing force on the matrix is reduced, and the distance between the lamellae expands.
