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Blue rubber bleb nevus syndrome causing refractory anaemia
Indira Maisnam1, Tanima Das, Arup K Kundu
1Department of Medicine, R. G. Kar Medical College, Kolkata 700004, West Bengal.
The Journal of the Association of Physicians of India
|November 5, 2010
Summary
Blue Rubber Bleb Nevus Syndrome (BRBNS) can cause recurrent gastrointestinal bleeding, leading to anemia. Increased physician awareness is crucial for early detection of this rare vascular disorder.
Area of Science:
- Vascular Malformations
- Gastroenterology
- Hematology
Background:
- Blue Rubber Bleb Nevus Syndrome (BRBNS) is a rare genetic disorder.
- It is characterized by widespread venous malformations in the skin and gastrointestinal tract.
Observation:
- Patients with BRBNS often present with gastrointestinal bleeding.
- This bleeding can lead to significant iron-deficiency anemia.
Findings:
- Recurrent melaena (dark, tarry stools) is a key indicator of gastrointestinal bleeding in BRBNS.
- The venous malformations are the underlying cause of hemorrhage.
Implications:
- Heightened physician awareness of BRBNS is essential for timely diagnosis.
- Early detection can prevent severe complications like profound anemia and facilitate appropriate management.
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