Related Experiment Video

Updated: Jun 7, 2026

Visualization of Bacterial Resistance using Fluorescent Antibiotic Probes
08:23

Visualization of Bacterial Resistance using Fluorescent Antibiotic Probes

Published on: March 2, 2020

Design and synthesis of phthalimide-based fluorescent liver x receptor antagonists

Kenji Kishida1, Atsushi Aoyama, Yuichi Hashimoto

  • 1Okayama University, Japan.

Chemical & Pharmaceutical Bulletin
|November 5, 2010
PubMed

Abstract:

Based on our structure-activity relationship study of liver X receptor (LXR) ligands, we designed and synthesized fluorescent LXR antagonists containing an unsubstituted or substituted amino group on a phthalimide unit.

More Related Videos

Synthesis of pH Dependent Pyrazole, Imidazole, and Isoindolone Dipyrrinone Fluorophores using a Claisen-Schmidt Condensation Approach
14:11

Synthesis of pH Dependent Pyrazole, Imidazole, and Isoindolone Dipyrrinone Fluorophores using a Claisen-Schmidt Condensation Approach

Published on: June 10, 2021

Preparation of N-(2-alkoxyvinyl)sulfonamides from N-tosyl-1,2,3-triazoles and Subsequent Conversion to Substituted Phthalans and Phenethylamines
10:42

Preparation of N-(2-alkoxyvinyl)sulfonamides from N-tosyl-1,2,3-triazoles and Subsequent Conversion to Substituted Phthalans and Phenethylamines

Published on: January 3, 2018

Related Experiment Videos

Last Updated: Jun 7, 2026

Visualization of Bacterial Resistance using Fluorescent Antibiotic Probes
08:23

Visualization of Bacterial Resistance using Fluorescent Antibiotic Probes

Published on: March 2, 2020

Synthesis of pH Dependent Pyrazole, Imidazole, and Isoindolone Dipyrrinone Fluorophores using a Claisen-Schmidt Condensation Approach
14:11

Synthesis of pH Dependent Pyrazole, Imidazole, and Isoindolone Dipyrrinone Fluorophores using a Claisen-Schmidt Condensation Approach

Published on: June 10, 2021

Preparation of N-(2-alkoxyvinyl)sulfonamides from N-tosyl-1,2,3-triazoles and Subsequent Conversion to Substituted Phthalans and Phenethylamines
10:42

Preparation of N-(2-alkoxyvinyl)sulfonamides from N-tosyl-1,2,3-triazoles and Subsequent Conversion to Substituted Phthalans and Phenethylamines

Published on: January 3, 2018

Related Concept Videos

Photoluminescence: Applications01:14

Photoluminescence: Applications

Photoluminescence offers a wide range of applications due to its inherent sensitivity and selectivity. This technique allows for both direct and indirect analyses of the analyte. Direct quantitative analysis is possible when the analyte exhibits a favorable quantum yield for fluorescence or phosphorescence. However, an indirect analysis may be feasible if the analyte is not fluorescent or phosphorescent, or if the quantum yield is unfavorable. Indirect methods include reacting the analyte with...

Articles linked to this work by shared authors, journal, and citation graph.

Synthesis of DNA-Encoded Libraries by Tryptophan-Selective Bioconjugation.

Organic letters·2026

On-DNA Platform Molecules Based on a Diazide Scaffold II: A Compact Diazide Platform Designed for Small-Molecule Drug Discovery.

International journal of molecular sciences·2026

Development of an On-DNA Platform Molecule Bearing a Diazidestructure and Its Application to DEL Synthesis.

International journal of molecular sciences·2025

Phthalimide: a potential warhead for switchable and bioorthogonal conjugation.

Chemical communications (Cambridge, England)·2025

Photo-Enhanced Aqueous Solubilization of Azobenzene-Incorporated Lipids.

Chemical & pharmaceutical bulletin·2025

Channel- and Label-Flip Data Augmentation for Motor Imagery-Based Brain-Computer Interfaces.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2025

Effect of Carbon-Chain Length in [125I]iodophenyl and [211At]astatophenyl Derivatives on Prostate-Specific Membrane Antigen-Targeted Radioligands.

Chemical & pharmaceutical bulletin·2026

Influence of pH, Alcohol Structure, and Temperature on Lenalidomide Alcoholysis with Implications for Pharmaceutical Quality Control.

Chemical & pharmaceutical bulletin·2026

Synthesis of CH2-Linked Isomaltose via α-Selective Photoredox Vinyl C-Glycosylation.

Chemical & pharmaceutical bulletin·2026

Structural Characterization of New 8,17-Epoxybriarane Diterpenoids from the Octocoral Briareum stechei.

Chemical & pharmaceutical bulletin·2026

High-Affinity Anti-nivolumab DNA Aptamer: A Novel Capture Reagent for Its Bioanalysis by an Enzyme-Linked Aptamer Assay.

Chemical & pharmaceutical bulletin·2026

Photoaffinity Electrophoretic Mobility Shift Assay for Analyzing the Binding Specificity of DNA Aptamers to α-Thrombin.

Chemical & pharmaceutical bulletin·2026

Three privileged scaffolds, one pipeline: chalcones, pyrazolines and pyrazoles in drug discovery and fluorescent sensing.

RSC medicinal chemistry·2026

Green, one-pot strategy for substitution of the 5-position of 1,10-phenanthrolines.

RSC advances·2026

ToxCompl Completion of the DrugMatrix Toxicogenomics Database: An Integrated Resource for Toxicological Hypothesis Generation.

Toxicological sciences : an official journal of the Society of Toxicology·2026

Guanxinkang Decoction and Its Key Component Isotanshinone II Ameliorate Atherosclerosis Through Modulation of STAT3/ CD36 Signaling and Macrophage Efferocytosis: An Integrated Network Pharmacology and Experimental Validation Study.

Combinatorial chemistry & high throughput screening·2026

Mechanism of Shao Kuiling Decoction in Treating Ulcerative Colitis: A Network Pharmacology and Molecular Docking Study.

Current computer-aided drug design·2026
See all related articles
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies
Jove
Visualize
Contact Us