Related Experiment Video
Updated: Jun 7, 2026

Non-Intubated Video-Assisted Thoracoscopic Surgery
Published on: May 26, 2023
Regional intravenous anesthesia in knee arthroscopy
Mahmut Arslan1, Mehmet Cantürk, Dilşen Ornek
1Ankara Numune Training and Research Hospital, Turkey.
Regional intravenous anesthesia for knee arthroscopy may be inadequate for high BMI patients. Adding ketamine to prilocaine may improve sensory block onset and extend pain relief duration.
Area of Science:
- Anesthesiology
- Orthopedic Surgery
- Pharmacology
Background:
- Regional intravenous anesthesia is a common technique for knee arthroscopy.
- High body mass index (BMI) may impact anesthetic effectiveness.
- Ketamine is sometimes used as an adjunct in regional anesthesia.
Purpose of the Study:
- To investigate regional intravenous anesthesia in knee arthroscopy.
- To evaluate the effect of adding ketamine to prilocaine on anesthesia block characteristics and tourniquet pain.
Main Methods:
- Forty American Society of Anesthesiologists (ASA) II patients undergoing knee arthroscopy were enrolled.
- Patients received either 0.5% prilocaine or prilocaine with ketamine via intravenous regional anesthesia.
- Key outcomes included sensory block onset/duration, tourniquet pain, analgesic consumption, and hemodynamic parameters.
Main Results:
- Higher BMI was associated with patients requiring general anesthesia.
- The ketamine group (Group PK) showed a shorter sensory block onset time.
- The ketamine group also demonstrated a longer time to first analgesic requirement.
Conclusions:
- Standard doses of regional intravenous anesthesia may be insufficient for knee arthroscopy in patients with high BMI.
- Adding ketamine to prilocaine may enhance sensory block onset and prolong the duration of analgesia.
- Further research may explore optimized anesthetic protocols for patients with elevated BMI.
More Related Videos
Related Concept Videos
Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia
One of the advantages of...
Local Anesthetics: Clinical Application as Epidural Anesthesia
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
Local Anesthetics: Clinical Application as Spinal Anesthesia
Parenteral Anesthetics: Overview
General Anesthesia: Overview
General anesthesia induces unconsciousness in the whole body, while the others target specific areas or sensations. It is administered to minimize adverse effects, maintain...
Local Anesthetics: Clinical Application as Surface, Infiltration, and Conduction Block Anesthesia
