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Optimization of the Epimedii Folium Mutton-Oil Processing Technology and Testing Its Effect on Zebrafish Embryonic Development
Published on: March 17, 2023
[Quality research on Epimedium cut crude drug processed with oil]
E Sun1, Xiao-Bin Jia, Xiao-Yong Jin
1Key Laboratory of New Drug Delivery System of Chinese Meteria Medica/The Key Unit of Chinese Medicine DDS of SATCM, Jiangsu Provincial Academy of Chinese Medicine, Nanjing 210028, China. sune0825@yahoo.com.cn
Objective:
To study internal quality of 14 batches Epimedium cut crude drug processed with oil, and to provide informations for quality specification in Chinese Pharmacopeia of 2010 edition.
Methods:
14 batches Epimedium cut crude drug processed with oil were investigated impurity, moisture content, total ash, acid-insoluble ash, extractum and assaying to analyze and evaluate their quality condition.
Results:
It is suggested that, in Epimedium cut crude drug processed with oil, the moisture content should not pass 8.0%, total ash should not pass 8.0%, acid-insoluble ash should not pass 2.0%, extractum content should not lower than 12.0%, total flavonoids content should not lower than 5.0%, icariin content should not lower than 0.6%, and Baohuoside I content should not lower than 0.1%.
Conclusion:
Quality evaluation system of Epimedium cut crude drug processed with oil has been constructed initially, it will offer scientific basis for instituting quality specification in Chinese Pharmacopeia of 2010 edition.
