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Related Experiment Video

Updated: Jun 7, 2026

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data

Published on: December 9, 2015

Injectable disease-modifying therapy for relapsing-remitting multiple sclerosis: a review of adherence data.

Christina Caon¹, Carol Saunders, Jennifer Smrtka

¹Multiple Sclerosis Center at Wayne State University School of Medicine, Detroit, MI, USA. crcaon@med.wayne.edu

The Journal of Neuroscience Nursing : Journal of the American Association of Neuroscience Nurses

|November 6, 2010

Summary

Long-term adherence to disease-modifying therapy for relapsing-remitting multiple sclerosis (RRMS) improves patient outcomes. Nursing interventions can enhance adherence, positively impacting the disease course for RRMS patients.

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A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data

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Published on: December 9, 2015

Dynamic Adhesion Assay for the Functional Analysis of Anti-adhesion Therapies in Inflammatory Bowel Disease

Dynamic Adhesion Assay for the Functional Analysis of Anti-adhesion Therapies in Inflammatory Bowel Disease

Published on: September 20, 2018

Area of Science:

Neurology
Patient Adherence Research

Background:

Long-term adherence to disease-modifying therapy (DMT) in relapsing-remitting multiple sclerosis (RRMS) is crucial for improved patient outcomes.
The unpredictable nature of RRMS, even with treatment, poses challenges to maintaining patient adherence.
Nonadherence can negatively impact disease course and quality of life.

Purpose of the Study:

To summarize the prevalence and impact of nonadherence to DMT in RRMS.
To review factors affecting treatment adherence in RRMS patients.
To explore nursing interventions that can improve adherence.

Main Methods:

Literature review of studies on adherence in RRMS.
Analysis of factors identified in clinical trials affecting adherence.
Summary of evidence for nursing interventions.

Main Results:

Nonadherence is prevalent and negatively impacts RRMS outcomes.
Various patient- and disease-related factors influence adherence.
Nursing interventions like telephone counseling and motivational interviewing show promise in improving adherence.

Conclusions:

Improving adherence to DMT is essential for managing RRMS.
Targeted nursing interventions can effectively address adherence barriers.
Enhanced adherence through nursing support can lead to better disease management and quality of life for RRMS patients.