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A Simplified and Efficient Method to Isolate Primary Human Keratinocytes from Adult Skin Tissue
Published on: August 25, 2018
Multiple minute digitate hyperkeratosis: a proposed algorithm for the digitate keratoses.
Tony Philip Caccetta1, Ben Dessauvagie, Dugald McCallum
1Department of Dermatology, Royal Perth Hospital, Perth, Australia. tony.caccetta@gmail.com
Journal of the American Academy of Dermatology
|November 6, 2010
Summary
Multiple minute digitate hyperkeratosis (MMDH) is a rare skin condition. This study presents a case and proposes a diagnostic algorithm for various digitate keratoses, aiding in classification and diagnosis.
Area of Science:
- Dermatology
- Keratinization disorders
- Rare diseases
Background:
- Multiple minute digitate hyperkeratosis (MMDH) is a rare disorder of keratinization.
- It is known by many different names in medical literature.
Observation:
- A case of MMDH in an 89-year-old woman is presented.
- A comprehensive literature search was performed using PubMed and MEDLINE.
- Key search terms included various digitate keratoses and their synonyms.
Findings:
- The study reviews and classifies digitate keratoses, including MMDH, lichen spinulosus, and others.
- A diagnostic algorithm is proposed to differentiate these conditions.
- Synonymous terms for digitate keratoses are tabulated.
Implications:
- Further research, including keratin analysis and genetic studies, may reveal distinct disease entities within digitate keratoses.
- The proposed diagnostic algorithm offers a clinical approach for identifying these rare conditions.
