[Transfusion in palliative care in child with malignant disease]

Transfusion occupies an important part of medical care in the palliative phase of paediatric malignancies with major bone marrow involvement. The aim of transfusion is to improve the quality of life. Fatigue is a frequent symptom in palliative phase, in children as well as in adults; anaemia is one of the responsible factor. Transfusion of red blood cells may contribute to the improvement this symptom. Specific pediatric recommendations are lacking, but studies in adults and clinical experience allow thinking that we should take into account the evaluation of this fatigue, more than a threshold value of haemoglobin. Platelets transfusion indication depends on the preserved activity and mobility of the child. The possibility of transfusion at home should reduce the constraints of this care.