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Updated: Jun 7, 2026

Minimally Invasive Murine Laryngoscopy for Close-Up Imaging of Laryngeal Motion During Breathing and Swallowing
Published on: December 1, 2023
Diagnostic criteria for the classification of vocal cord dysfunction
Michael J Morris1, Kent L Christopher
1Department of Medicine (MCHE-MD), 3851 Roger Brooke Dr, Brooke Army Medical Center, Ft. Sam Houston, TX 78234-6200, USA. michael.morris@amedd.army.mil
Vocal cord dysfunction (VCD) causes breathing problems due to vocal cord spasms. This review clarifies VCD diagnosis, differentiating it from other airway issues and exploring its causes.
Area of Science:
- Laryngology
- Pulmonology
- Clinical Medicine
Background:
- Vocal cord dysfunction (VCD) is a poorly understood syndrome of glottic obstruction.
- It presents with dyspnea and noisy breathing, often misdiagnosed as asthma.
- Existing literature shows disparities in understanding its etiology, pathophysiology, and management.
Purpose of the Study:
- To review current evidence on VCD.
- To propose an approach for VCD evaluation.
- To differentiate VCD from other upper airway disorders.
Main Methods:
- In-depth review of retrospective and prospective medical literature.
- Analysis of factors associated with VCD.
- Examination of differential diagnoses for upper airway movement disorders.
Main Results:
- VCD requires differentiation from conditions like laryngomalacia and vocal cord paresis.
- Associated factors include psychological origins, GERD, irritants, and exercise.
- Clinical, spirometric, and endoscopic criteria are crucial for diagnosis.
Conclusions:
- A structured approach is needed for VCD evaluation.
- Accurate diagnosis requires differentiating VCD from other laryngeal conditions.
- Further prospective studies are needed to clarify VCD's complex nature.
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