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Related Concept Videos

Antidepressant Drugs: MAOIs and Other Agents01:23

Antidepressant Drugs: MAOIs and Other Agents

Atypical antidepressants, including bupropion (Wellbutrin), mirtazapine (Remeron), nefazodone (Serzone), trazodone (Desyrel), and vilazodone (Viibryd), offer unique mechanisms of action. Bupropion weakly inhibits dopamine and norepinephrine reuptake, aiding depression treatment and smoking cessation, with a low risk of sexual dysfunction. Mirtazapine enhances serotonin and norepinephrine neurotransmission, leading to sedation, increased appetite, and weight gain. As a result, it helps treat...
Antidepressant Drugs: Overview01:25

Antidepressant Drugs: Overview

Antidepressant drugs are a class of medications primarily used for treating various mood disorders, including major depression, anxiety disorders, and other related conditions. These medicines work by modulating the neurotransmitter balance within the brain, alleviating depressive symptoms. Antidepressants can be broadly categorized into several groups according to their mechanism of action and chemical structure: Selective Serotonin Reuptake Inhibitors (SSRIs), Serotonin-Norepinephrine...
Continuing Care01:25

Continuing Care

Continuing care describes the variety of health, personal, and social services provided over a prolonged period. The need for continuing care is increasing because people are living longer. Many people do not have families or others to care for them. Continuing care is mainly for patients who are disabled, functionally dependent, or suffering from a terminal disease. It is available within institutional settings or in homes. Examples include nursing centers or facilities, assisted living,...
Antidepressant Drugs: Tricyclics, SSRIs, and SNRIs01:28

Antidepressant Drugs: Tricyclics, SSRIs, and SNRIs

Tricyclic Antidepressants (TCAs), including Desipramine (Norpramin), Imipramine (Tofranil), Clomipramine (Anafranil), and Amitriptyline (Elavil), inhibit serotonin and norepinephrine reuptake and also block other receptors. They are used for depression, pain conditions, and insomnia. Common adverse effects include anticholinergic effects, sedation, orthostatic hypotension, and weight gain. They have a narrow therapeutic window and so require plasma-level monitoring. Abrupt discontinuation can...
Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
Prescription, Nonprescription and Orphan Drugs01:02

Prescription, Nonprescription and Orphan Drugs

Prescription drugs require a prescription from a medical practitioner and can only be obtained from a pharmacy. They have many applications, including treating pain, anxiety, and hypertension.
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Updated: Jun 7, 2026

Therapeutic Massage for Psychological Well-being in Geriatric Oncology
03:59

Therapeutic Massage for Psychological Well-being in Geriatric Oncology

Published on: May 22, 2026

Antidepressant prescription pattern in a hospice program.

Paulo R Shiroma1, Yonas E Geda, Amit Mohan

  • 1Geriatric Psychiatry Clinic, Mental Health Service Line, Minneapolis VA Medical Center, Minneapolis, MN 55417, USA. pshiroma@umn.edu

The American Journal of Hospice & Palliative Care
|November 6, 2010
PubMed
Summary
This summary is machine-generated.

Treatable depression affects up to 25% of terminally ill patients. This study found an 11.7% incidence of antidepressant use in hospice care, with longer survival predicting higher likelihood of treatment.

Related Experiment Videos

Last Updated: Jun 7, 2026

Therapeutic Massage for Psychological Well-being in Geriatric Oncology
03:59

Therapeutic Massage for Psychological Well-being in Geriatric Oncology

Published on: May 22, 2026

Area of Science:

  • Palliative Care
  • Psychiatry
  • Gerontology

Background:

  • Depression is prevalent in terminally ill patients, affecting up to 25% of this population.
  • Effective treatments for depression exist, yet their utilization in palliative care settings requires further investigation.

Purpose of the Study:

  • To determine the incidence of antidepressant use among patients in a hospice program.
  • To identify factors associated with antidepressant prescription in terminally ill patients.

Main Methods:

  • Retrospective cohort study at the Mayo Hospice Program (June 2007 - December 2008).
  • Analysis of patient records to ascertain antidepressant use and associated clinical factors.
  • Statistical analysis to estimate cumulative probability and identify predictors of antidepressant receipt.

Main Results:

  • The 18-month cumulative probability of receiving an antidepressant during hospice was 11.7%.
  • Depression was the most common indication for antidepressant use, with selective serotonin reuptake inhibitors (SSRIs) being the most frequently prescribed class.
  • Increased survival in hospice was a significant predictor for receiving an antidepressant (OR=2.71).

Conclusions:

  • Antidepressant utilization in hospice care is notable but may be suboptimal given the prevalence of treatable depression.
  • Further research is needed to improve diagnostic tools, patient education on antidepressant benefits in palliative care, and establish clear prescribing guidelines.