Related Experiment Video
Updated: Jun 6, 2026

Ookluc: A Plasmodium berghei Line for Identifying Transmission-blocking Compounds
Published on: July 11, 2025
Abstract:
Malaria is a potentially life-threatening disease caused by protozoal parasites of the genus Plasmodium. It is mainly a problem in developing countries, and cases in the UK involve travellers coming from endemic areas. Resistance is increasing to several antimalarial drugs (e.g. chloroquine, mefloquine, antifolates). Another group of drugs, known as artemisinins, have come into widespread use more recently. An oral artemisinin-combination therapy (ACT) is now one of the standard licensed treatments for uncomplicated malaria in the UK. However, the parenteral artemisinin for severe malaria, artesunate, is not licensed in developed countries. Here we consider the role of artemisinins as treatment for malaria in the UK.
Related Concept Videos
Anthelminthic Agents
Malaria
Antiprotozoal Agents
Venous Thrombosis III: Interprofessional Care
Treatment for Pulmonary Arterial Hypertension: Endothelin Receptor Antagonists
ETs are synthesized through a complex sequence of enzymatic steps, primarily involving an enzyme referred to as endothelin-converting enzyme (ECE). Of...
Antiasthma Drugs: Muscarinic Receptor Antagonists
Antimuscarinic agents compete with ACh for the same binding site on the muscarinic receptors. By binding to these receptors, they inhibit the downstream effects of ACh and block the parasympathetic...

