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The mouse Gene Expression Database (GXD): 2011 update.

Jacqueline H Finger¹, Constance M Smith, Terry F Hayamizu

¹The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA.

Nucleic Acids Research

|November 11, 2010

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The Gene Expression Database (GXD) provides integrated mouse developmental expression data at transcript and protein levels. This resource enhances biological context through connections with other databases and improved search functionalities.

Area of Science:

Developmental Biology
Genomics
Bioinformatics

Background:

The Gene Expression Database (GXD) is a vital community resource for mouse developmental expression information.
It integrates diverse expression data, including transcript and protein levels, across various mouse strains and mutants.

Purpose of the Study:

To present updates and improvements to the Gene Expression Database (GXD).
To highlight enhanced data integration, improved user interface, and expanded querying capabilities.

Main Methods:

Data integration from literature, individual laboratories, and large-scale providers.
Annotation and curation of expression data by GXD curators.
Development of web-based query forms for data retrieval.

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Main Results:

Significant increase in GXD data content since the last report.
Improvements in the user interface and data visualization.
Implementation of new querying capabilities and enhanced links to other expression resources.

Conclusions:

The Gene Expression Database (GXD) continues to be a comprehensive and evolving resource for mouse developmental expression data.
Enhanced integration and accessibility facilitate deeper biological insights and research.
The resource is readily available via the Mouse Genome Informatics (MGI) website.