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Updated: Jun 6, 2026

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Translational Rabbit Model of Chronic Cardiac Pacing
Published on: January 6, 2023
Safety and performance of a system specifically designed for selective site pacing
Francesco Zanon1, Carla Svetlich, Eraldo Occhetta
1Division of Cardiology, Ospedale Santa Maria della Misericordia, Rovigo, Italy. franc.zanon@iol.it
Pacing and Clinical Electrophysiology : PACE
|November 13, 2010
Summary
Selective site pacing (SSP) using the Select Secure System™ offers a versatile approach for pacing in the right atrium, right ventricle, and His-bundle region, demonstrating successful implantation and good pacing parameters.
Area of Science:
- Cardiology
- Electrophysiology
- Medical Devices
Background:
- Selective site pacing (SSP) in the right ventricle mitigates adverse hemodynamic effects of apical pacing.
- Right atrial SSP can prevent atrial fibrillation and slow disease progression.
Purpose of the Study:
- To describe the clinical use of a transvenous 4-French catheter-delivered lead for SSP.
- To evaluate the feasibility and outcomes of SSP across multiple centers.
Main Methods:
- A multicenter observational study enrolled 574 patients indicated for an implantable device.
- Selective site pacing was achieved using the Select Secure System™.
Main Results:
- Lead implantation was successful in 570 patients.
- SSP was performed in the atrium (interatrial septum, coronary sinus, Bachman bundle), ventricle (RVOT), and His-bundle region (direct or para-Hisian).
- A lead-related complication rate of 2.6% was observed during a mean follow-up of 20 months.
Conclusions:
- The Select Secure System™ enables effective pacing at various sites within the right atrium, right ventricle, and His-bundle region.
- This system facilitates diverse selective site pacing strategies in clinical practice.
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