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Cutaneous metastases from hepatomas.

I M Reingold, B R Smith

    Archives of Dermatology
    |July 1, 1978
    PubMed
    Summary
    This summary is machine-generated.

    Skin metastases from hepatomas are rare but can appear as unusual nodules. Biopsies confirmed these cutaneous metastases, often preceding the primary liver tumor diagnosis.

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    Area of Science:

    • Oncology
    • Dermatology
    • Pathology

    Background:

    • Hepatoma (liver cancer) can metastasize to various organs.
    • Cutaneous metastases are uncommon but significant indicators of advanced malignancy.

    Observation:

    • Three cases of hepatoma with skin metastasis were identified among 88 patients.
    • Skin lesions presented as sudden, firm, reddish-blue nodules on the scalp, chest, and shoulder.
    • These nodules were distinct from common benign skin lesions.

    Findings:

    • Biopsies confirmed skin tumors as cutaneous metastases of hepatoma.
    • Histopathology revealed adenocarcinoma in two cases and hepatocellular carcinoma in one.
    • In these cases, skin metastasis preceded the diagnosis of the primary liver tumor.

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    Implications:

    • Cutaneous metastases of hepatoma can be an early sign of unrecognized primary liver cancer.
    • The appearance of such nodules warrants thorough investigation for underlying malignancy.
    • Skin metastasis signifies advanced disease with a poor prognosis, often preceding death within months.