Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

RNA-seq03:21

RNA-seq

RNA sequencing, or RNA-Seq, is a high-throughput sequencing technology used to study the transcriptome of a cell. Transcriptomics helps to interpret the functional elements of a genome and identify the molecular constituents of an organism. Additionally, it also helps in understanding the development of an organism and the occurrence of diseases. 
Before the discovery of RNA-seq, microarray-based methods and Sanger sequencing were used for transcriptome analysis. However, while microarray-based...
DNA Microarrays02:34

DNA Microarrays

Microarrays are high-throughput and relatively inexpensive assays that can be automated to analyze large quantities of data at a time. They are used in genome-wide studies to compare gene or protein expression under two varied conditions, such as healthy and diseased states. Microarrays consist of glass or silica slides on which probe molecules are covalently attached through surface functionalization. Most commonly, the slides are prepared through the chemisorption of silanes to silica...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Programmatic access to ICTV virus taxonomy through a public ontology API.

bioRxiv : the preprint server for biology·2026
Same author

scDenorm: a denormalization tool for integrating single-cell transcriptomics data.

GigaScience·2026
Same author

Peer support intervention (ABA-feed) to improve breastfeeding: UK based, multicentre, parallel group, randomised controlled trial.

BMJ (Clinical research ed.)·2026
Same author

Correction: Establishing standardized transthoracic echocardiography reference ranges for mouse models: insights into the impact of anesthesia, sex, and age.

Frontiers in cardiovascular medicine·2026
Same author

Topological Data Analysis for Unsupervised Feature Selection in Large Scale Spatial Omics Data Sets.

Bulletin of mathematical biology·2026
Same author

Why are some cases not on track? An investigation of common obstacles and solutions during feedback-informed psychological therapy.

Journal of consulting and clinical psychology·2026
Same journal

Correction to 'New origin firing is inhibited by APC/CCdh1 activation in S-phase after severe replication stress'.

Nucleic acids research·2026
Same journal

VeloRM: disentangling pre- and post-splicing RNA modification dynamics at single-cell resolution.

Nucleic acids research·2026
Same journal

Accessibility of telomeric overhangs to stabilizing small-molecule ligands.

Nucleic acids research·2026
Same journal

Multivalent interactions mediate SNAIL transcription factor stimulation of the nucleosome deacetylase activity of the CoREST complex.

Nucleic acids research·2026
Same journal

Genome-wide mapping of DNA G-quadruplexes in Trypanosoma brucei chromatin reveals enrichment in coding regions and transcription start sites.

Nucleic acids research·2026
Same journal

Correction to 'The Gene Ontology knowledgebase in 2026'.

Nucleic acids research·2026
See all related articles

Related Experiment Video

Updated: Jun 6, 2026

Comprehensive Workflow for the Genome-wide Identification and Expression Meta-analysis of the ATL E3 Ubiquitin Ligase Gene Family in Grapevine
10:40

Comprehensive Workflow for the Genome-wide Identification and Expression Meta-analysis of the ATL E3 Ubiquitin Ligase Gene Family in Grapevine

Published on: December 22, 2017

ArrayExpress update--an archive of microarray and high-throughput sequencing-based functional genomics experiments.

Helen Parkinson1, Ugis Sarkans, Nikolay Kolesnikov

  • 1Functional Genomics Team, EMBL-EBI, Wellcome Trust Genome Campus, Hinxton CB10 1SD, UK. parkinson@ebi.ac.uk

Nucleic Acids Research
|November 13, 2010
PubMed
Summary
This summary is machine-generated.

The ArrayExpress Archive is a public repository for functional genomics data from sequencing and array-based technologies. It supports publications and integrates with other bioinformatics resources for advanced data querying.

More Related Videos

Targeted RNA Sequencing Assay to Characterize Gene Expression and Genomic Alterations
11:52

Targeted RNA Sequencing Assay to Characterize Gene Expression and Genomic Alterations

Published on: August 4, 2016

Related Experiment Videos

Last Updated: Jun 6, 2026

Comprehensive Workflow for the Genome-wide Identification and Expression Meta-analysis of the ATL E3 Ubiquitin Ligase Gene Family in Grapevine
10:40

Comprehensive Workflow for the Genome-wide Identification and Expression Meta-analysis of the ATL E3 Ubiquitin Ligase Gene Family in Grapevine

Published on: December 22, 2017

Targeted RNA Sequencing Assay to Characterize Gene Expression and Genomic Alterations
11:52

Targeted RNA Sequencing Assay to Characterize Gene Expression and Genomic Alterations

Published on: August 4, 2016

Area of Science:

  • Bioinformatics
  • Functional Genomics
  • Data Archiving

Background:

  • ArrayExpress is a key international public repository for functional genomics data.
  • It supports data from sequencing and array-based technologies, crucial for publication.
  • Data is sourced from user submissions and the NCBI Gene Expression Omnibus.

Purpose of the Study:

  • To describe the ArrayExpress Archive as a public functional genomics data repository.
  • To highlight its integration with other bioinformatics resources.
  • To detail its advanced querying capabilities based on sample attributes.

Main Methods:

  • Data submission by users.
  • Direct import from NCBI Gene Expression Omnibus.
  • Integration with Gene Expression Atlas and European Bioinformatics Institute sequence databases.
  • Ontology-enabled interfaces for advanced queries.

Main Results:

  • ArrayExpress serves as a major public repository for functional genomics data.
  • It offers integrated access to diverse functional genomics datasets.
  • Advanced search functionalities enable detailed data exploration based on experimental attributes.

Conclusions:

  • The ArrayExpress Archive is a vital resource for functional genomics data sharing and accessibility.
  • Its integration and advanced querying features enhance data discoverability and utility for researchers.
  • It plays a crucial role in supporting scientific publications through robust data archiving.