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Updated: Jun 6, 2026
05:41
2D-HELS MS Seq: A General LC-MS-Based Method for Direct and de novo Sequencing of RNA Mixtures with Different Nucleotide Modifications
Published on: July 10, 2020
The RNA Modification Database, RNAMDB: 2011 update.
William A Cantara1, Pamela F Crain, Jef Rozenski
1The RNA Institute, University at Albany, State University of New York, 1400 Washington Avenue, Albany, NY 12222, USA.
Nucleic Acids Research
|November 13, 2010
Summary
The RNA Modification Database (RNAMDB) catalogs 109 RNA modifications, offering detailed chemical and biological data. It continues to expand, serving as a vital resource for RNA research.
Area of Science:
- Biochemistry
- Molecular Biology
- Bioinformatics
Background:
- The RNA Modification Database (RNAMDB) has been a key resource since 1994 for information on naturally occurring RNA modifications.
- It provides a searchable interface with data on 109 known RNA modifications.
Purpose of the Study:
- To provide a comprehensive and accessible resource for RNA modification data.
- To highlight recent updates and future expansion plans for the RNAMDB.
Main Methods:
- The database utilizes a searchable interface to present detailed information on RNA modifications.
- Data includes chemical structure, nomenclature, elemental composition, phylogenetic source, and RNA species.
Main Results:
- The RNAMDB currently details 109 RNA modifications.
- Recent additions include agmatidine and 8-methyladenosine.
- The database is undergoing improvements and expansion.
Conclusions:
- The RNAMDB remains a crucial, growing resource for RNA modification information.
- Future enhancements will solidify its role as a primary portal for RNA researchers.
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