Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Formation of Lipopolysaccharides01:19

Formation of Lipopolysaccharides

Lipopolysaccharides (LPS) are crucial components of the outer membrane of Gram-negative bacteria, serving both structural and functional roles. It contributes to membrane stability and protects bacteria from host immune responses. LPS is composed of three major regions—lipid A, a core oligosaccharide, and an O antigen. The biosynthesis and assembly of LPS involve a highly coordinated set of enzymatic reactions and transport mechanisms. Additionally, LPS is recognized as an endotoxin, triggering...
Site-Targeted Drug Delivery Systems: Polymeric Carriers01:24

Site-Targeted Drug Delivery Systems: Polymeric Carriers

Polymeric carriers enhance targeted drug delivery by increasing efficacy while minimizing off-target effects. These carriers comprise a biodegradable polymeric backbone integrated with functional elements that enable targeting, improve physicochemical properties, and regulate drug release.Targeting MechanismsThe targeting ability of polymeric carriers is mediated by a homing device, which is a molecular recognition component designed to selectively bind to specific tissues or cells. Monoclonal...
Oligosaccharide Assembly01:24

Oligosaccharide Assembly

Protein glycosylation starts in the ER lumen and continues in the Golgi apparatus. Glycosyltransferases catalyze the addition of sugar molecules or glycosylation of proteins. Usually, these enzymes add sugars to the hydroxyl groups of selected serine or threonine residues to form O-linked glycans or the amino groups of asparagine residues to form N-linked glycans. Different positions on the same polypeptide chain can contain differently linked glycans.
Multiple sugar molecules that may or may...
COP Coated Vesicles00:59

COP Coated Vesicles

Membrane-enclosed structures called vesicles transport proteins and lipids across the cell. The vesicles derive their cargo from the plasma membrane, Golgi, ER, or endosome. Coated vesicles are spherical, protein-coated carriers with a 50–100 nm diameter that mediate bidirectional transport between the ER and the Golgi. The distribution of proteins between the ER and Golgi complex is dynamic and is maintained by different coated vesicles. Their formation is driven by the assembly of different...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A framework for building a synthetic cell from the SynCell Asia Initiative.

Nature biotechnology·2026
Same author

Supramolecular Assembly of Proteoliposomes Containing Photosensitizers Regulating Energy Synthesis.

Angewandte Chemie (International ed. in English)·2026
Same author

Amino Acid-based Coacervates with Tunable Stimulus-Responsive Properties for Enhanced Acute Colitis Therapy.

Advanced materials (Deerfield Beach, Fla.)·2026
Same author

Coupling Nanoarchitectonics with S-scheme heterojunction engineering for high-efficiency semi-artificial bio-photoelectrochemical systems.

Journal of colloid and interface science·2026
Same author

Nanoarchitectonics of peptide-silk fibroin hydrogel as a cell reservoir for volumetric muscle loss therapy.

Journal of colloid and interface science·2026
Same author

Proteoliposomes containing ATPase as microreactors to mimic microbial metabolism for bioenergy synthesis.

Journal of colloid and interface science·2026
Same journal

3-Methyleneazetidine: a versatile building block for functional and post-modifiable polysulfonamides.

Chemical communications (Cambridge, England)·2026
Same journal

Synthesis of divalent galactosyl and fucosyl spiropyran derivatives for the targeted inhibition of bacterial biofilms.

Chemical communications (Cambridge, England)·2026
Same journal

Emergent cytotoxicity and mitochondrial alterations induced by a heterobimetallic Re(I)/Au(I) complex.

Chemical communications (Cambridge, England)·2026
Same journal

Cyanoacetylation of amines <i>via</i> a traceless cyanoacetyl radical: synthetic access to teriflunomide.

Chemical communications (Cambridge, England)·2026
Same journal

Loading layered double hydroxide nanoarray catalysts on a micro-curved substrate for kinetics-favorable water electrolysis reaction.

Chemical communications (Cambridge, England)·2026
Same journal

Bridging <i>in situ</i> measurements and practical conditions through gas-liquid management for CO/CO<sub>2</sub> reduction.

Chemical communications (Cambridge, England)·2026
See all related articles

Related Experiment Video

Updated: Jun 6, 2026

Activation and Conjugation of Soluble Polysaccharides using 1-Cyano-4-Dimethylaminopyridine Tetrafluoroborate (CDAP)
07:20

Activation and Conjugation of Soluble Polysaccharides using 1-Cyano-4-Dimethylaminopyridine Tetrafluoroborate (CDAP)

Published on: June 14, 2021

pH-responsive polysaccharide microcapsules through covalent bonding assembly.

Yi Jia1, Jinbo Fei, Yue Cui

  • 1Beijing National Laboratory for Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China.

Chemical Communications (Cambridge, England)
|November 13, 2010
PubMed
Summary
This summary is machine-generated.

Researchers developed biocompatible microcapsules from polysaccharides. These pH-responsive, autofluorescent microcapsules show promise for biological tracing and drug delivery applications.

More Related Videos

High-throughput Synthesis of Carbohydrates and Functionalization of Polyanhydride Nanoparticles
14:37

High-throughput Synthesis of Carbohydrates and Functionalization of Polyanhydride Nanoparticles

Published on: July 6, 2012

Making Conjugation-induced Fluorescent PEGylated Virus-like Particles by Dibromomaleimide-disulfide Chemistry
10:18

Making Conjugation-induced Fluorescent PEGylated Virus-like Particles by Dibromomaleimide-disulfide Chemistry

Published on: May 27, 2018

Related Experiment Videos

Last Updated: Jun 6, 2026

Activation and Conjugation of Soluble Polysaccharides using 1-Cyano-4-Dimethylaminopyridine Tetrafluoroborate (CDAP)
07:20

Activation and Conjugation of Soluble Polysaccharides using 1-Cyano-4-Dimethylaminopyridine Tetrafluoroborate (CDAP)

Published on: June 14, 2021

High-throughput Synthesis of Carbohydrates and Functionalization of Polyanhydride Nanoparticles
14:37

High-throughput Synthesis of Carbohydrates and Functionalization of Polyanhydride Nanoparticles

Published on: July 6, 2012

Making Conjugation-induced Fluorescent PEGylated Virus-like Particles by Dibromomaleimide-disulfide Chemistry
10:18

Making Conjugation-induced Fluorescent PEGylated Virus-like Particles by Dibromomaleimide-disulfide Chemistry

Published on: May 27, 2018

Area of Science:

  • Biomaterials Science
  • Polymer Chemistry
  • Nanotechnology

Background:

  • Microcapsules are crucial for drug delivery and biological tracing.
  • Developing biocompatible and biodegradable materials is essential for advanced biomedical applications.
  • Polysaccharides offer a versatile platform for creating novel functional materials.

Purpose of the Study:

  • To fabricate biocompatible and biodegradable microcapsules using polysaccharides.
  • To impart autofluorescence and pH-responsivity to the microcapsules.
  • To explore the potential applications of these microcapsules in biological tracing and drug delivery.

Main Methods:

  • Covalent assembly of polysaccharides and their derivatives.
  • Utilizing Schiff's base formation for material synthesis.
  • Characterization of microcapsule properties, including autofluorescence and pH-responsivity.

Main Results:

  • Successfully fabricated biocompatible and biodegradable polysaccharide microcapsules.
  • Demonstrated autofluorescence and pH-responsive behavior due to Schiff's base formation.
  • Confirmed the integrity and functionality of the microcapsules for potential applications.

Conclusions:

  • Polysaccharide-based microcapsules can be effectively synthesized with tunable properties.
  • Schiff's base chemistry is a viable method for creating functional autofluorescent and pH-responsive biomaterials.
  • These novel microcapsules hold significant potential for advancing biological tracing and targeted drug delivery systems.