Related Experiment Video
Updated: Jun 6, 2026

In Vivo Infection with Leishmania amazonensis to Evaluate Parasite Virulence in Mice
Published on: February 20, 2020
Characterization of Leishmania spp. causing cutaneous leishmaniasis in Manaus, Amazonas, Brazil
Leila Ines Camara Coelho1, Marcilene Paes, Jorge Augusto Guerra
1Gerencia de Leishmanioses, Funbdação de Medicina Tropical do Amazonas, Manaus, Brazil. liarccoelho@yahoo.com.br
Abstract:
In the State of Amazonas, American tegumentary leishmaniasis is endemic and presents a wide spectrum of clinical variability due to the large diversity of circulating species in the region. Isolates from patients in Manaus and its metropolitan region were characterized using monoclonal antibodies and isoenzymes belonging to four species of the parasite: Leishmania (Viannia) guyanensis, 73% (153/209); Leishmania (Viannia) braziliensis, 14% (30/209); Leishmania (Leishmania) amazonensis, 8% (17/209); and Leishmania (Viannia) naiffii, 4% (9/209). The most prevalent species was L. (V.) guyanensis. The principal finding of this study was the important quantity of infections involving more than one parasite species, representing 14% (29/209) of the total. The findings obtained in this work regarding the parasite are further highlighted by the fact that these isolates were obtained from clinical samples collected from single lesions.
Related Concept Videos
Leishmaniasis
Antiprotozoal Agents
American Trypanosomiasis
Malaria
Amebiasis
