Related Experiment Video
Updated: Jun 6, 2026
07:36
Isolation of Human Lymphatic Endothelial Cells by Multi-parameter Fluorescence-activated Cell Sorting
Published on: May 1, 2015
[Localized cystic lymphatic malformation (or cutaneous lymphangiomas)]
Gérard Lorette1, Loïc Vaillant, Ewa Wiersbicka
1Université François-Rabelais de Tours, faculté de médecine, CHRU de Tours, Inserm U 930, 37044 Tours cedex 09, France. lorette@med.univ-tours.fr
Presse Medicale (Paris, France : 1983)
|November 16, 2010
Summary
Cutaneous cystic lymphatic malformations are lymphatic system dilatations with varied presentations. MRI best assesses deep lesions, guiding multidisciplinary treatment decisions for these complex vascular anomalies.
Area of Science:
- Vascular Anomalies
- Lymphatic System Development
- Dermatology
Context:
- Cutaneous cystic lymphatic malformations represent a spectrum of lymphatic system dilatations.
- Clinical presentations vary significantly in complexity and severity.
- Accurate diagnosis and staging are crucial for effective management.
Purpose:
- To outline the diagnostic utility of Magnetic Resonance Imaging (MRI) for deep lymphatic malformations.
- To summarize current therapeutic strategies based on lesion characteristics and location.
- To emphasize the role of multidisciplinary consultation in treatment planning.
Summary:
- Lymphatic malformations are classified based on size and morphology, impacting clinical course.
- MRI is the gold standard for evaluating the extent of deep-seated lesions.
- Treatment modalities include surgical excision for localized superficial forms and sclerotherapy as first-line for macrocystic types.
Impact:
- Improved diagnostic accuracy through advanced imaging techniques like MRI.
- Optimized patient outcomes via tailored, multidisciplinary treatment approaches.
- Enhanced understanding of lymphatic malformation management, differentiating superficial and deep forms.
Related Concept Videos
01:23Detailed Structure and Function of Lymph Nodes
Lymph nodes are bean-shaped structures that cluster along the lymphatic vessels in the inguinal, axillary, and cervical regions. Each node is divided into compartments by a capsule that extends trabeculae inward.
From a histological perspective, lymph nodes can be split into two main areas: the superficial cortex and the deep medulla. The outer cortex is populated by dendritic cells, macrophages, and B lymphocytes, which are densely packed into follicles. When these B-lymphocytes are presented...
From a histological perspective, lymph nodes can be split into two main areas: the superficial cortex and the deep medulla. The outer cortex is populated by dendritic cells, macrophages, and B lymphocytes, which are densely packed into follicles. When these B-lymphocytes are presented...
01:15Secondary Lymphoid Organs
Secondary organs, including lymph nodes, the spleen, and mucosa-associated lymphoid tissue (MALT), work harmoniously to protect us from disease and infection.
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...
01:15Development of the Lymphatic System
The development of lymphatic tissues and vessels in embryonic life begins around the fifth week. These structures originate from the mesoderm layer, with lymph sacs emerging from developing veins.
The first lymph sacs to form are the paired jugular lymph sacs located at the junction of the internal jugular and subclavian veins. From these sacs, lymphatic capillary plexuses extend to the thorax, upper limbs, neck, and head, eventually forming lymphatic vessels. Each jugular lymph sac maintains a...
The first lymph sacs to form are the paired jugular lymph sacs located at the junction of the internal jugular and subclavian veins. From these sacs, lymphatic capillary plexuses extend to the thorax, upper limbs, neck, and head, eventually forming lymphatic vessels. Each jugular lymph sac maintains a...
01:18Lymphoid Cells and Tissues
Lymphoid cells and tissues are integral to the immune system, which is crucial in maintaining our body's defense against harmful pathogens. They form the building blocks of lymphoid organs, which include the spleen, thymus, and lymph nodes.
Lymphoid cells consist of various types of immune system cells. These include B and T lymphocytes, which are responsible for producing antibodies and killing infected cells, respectively. Dendritic cells act as messengers between the innate and adaptive...
Lymphoid cells consist of various types of immune system cells. These include B and T lymphocytes, which are responsible for producing antibodies and killing infected cells, respectively. Dendritic cells act as messengers between the innate and adaptive...
01:30Skin Cancer
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
01:16Lymphatic Vessels and Lymph Transport
Lymphatic vessels, known as lymphatics, are crucial in transporting lymph from peripheral tissues to our venous system. This process begins with lymph entering through tiny capillaries that branch through tissues. These capillaries have unique features such as larger diameters, thinner walls, and a distinctive one-way valve system formed by overlapping endothelial cells.
This one-way system allows fluids, solutes, and even pathogens to enter but prevents their return to the intercellular spaces.
This one-way system allows fluids, solutes, and even pathogens to enter but prevents their return to the intercellular spaces.