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Updated: Jun 6, 2026

Identifying Coronary Artery Calcification on Non-gated Computed Tomography Scans
Published on: August 28, 2018
Ruling out coronary artery disease with noninvasive coronary multidetector CT angiography before noncoronary
Paz Catalán1, Rubén Leta, Alberto Hidalgo
1Cardiac Imaging Unit, Department of Cardiovascular Surgery and Cardiology, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Clínica Creu Blanca, Reina Elisenda de Montcada 17, Barcelona 08034, Spain. pcatalan@creu-blanca.es
Insights
Preoperative coronary computed tomographic angiography is useful for detecting coronary artery disease in patients undergoing noncoronary cardiovascular surgery. This imaging can safely avoid unnecessary invasive coronary angiography in many cases.
Area of Science:
- Cardiovascular Imaging
- Radiology
- Cardiac Surgery
Background:
- Coronary artery disease (CAD) assessment is crucial before noncoronary cardiovascular surgery.
- Invasive coronary angiography (ICA) is the gold standard but carries risks.
- Non-invasive imaging modalities are sought to optimize patient selection and reduce unnecessary procedures.
Purpose of the Study:
- To evaluate the diagnostic utility of preoperative coronary computed tomographic (CT) angiography.
- To determine its effectiveness in identifying coronary artery disease (CAD) in patients undergoing noncoronary cardiovascular surgery.
- To assess its role in potentially avoiding invasive coronary angiography (ICA).
Main Methods:
- Prospective study of 161 patients undergoing noncoronary cardiovascular surgery.
- Coronary calcium scoring and coronary CT angiography were performed preoperatively.
- Follow-up assessed ischemic events; multivariate analysis identified predictors of nondiagnostic CT angiography.
Main Results:
- Coronary CT angiography was diagnostic in 81% of 133 patients (108/133).
- 93% of patients with diagnostic CT angiography had no significant CAD and proceeded without ICA.
- The Agatston coronary calcium score was the sole independent predictor of nondiagnostic CT angiography (cutoff 579).
Conclusions:
- Preoperative coronary CT angiography is a valuable tool in nonselected patients undergoing noncoronary cardiovascular surgery.
- It can safely identify patients who do not require invasive coronary angiography.
- The Agatston score predicts the diagnostic quality of coronary CT angiography.
Purpose:
To assess the usefulness of preoperative coronary computed tomographic (CT) angiography in the detection of coronary artery disease (CAD) in nonselected patients scheduled to undergo noncoronary cardiovascular surgery to avoid unnecessary invasive coronary angiography (ICA).
Materials And Methods:
The institutional review board approved the study protocol; informed consent was given. This prospective study involved 161 consecutive patients who underwent coronary calcium scoring and coronary CT angiography before undergoing noncoronary cardiovascular surgery. Seven patients were excluded because of contraindications to CT angiography. The major indication of noncoronary cardiovascular surgery was valvular heart disease (121 patients). Follow-up was performed at a median of 20 months to define ischemic events described as acute coronary syndrome or death secondary to acute coronary syndrome, arrhythmias, or cardiac failure. Multivariate analysis was performed to determine predictors of nondiagnostic coronary CT angiography. Kaplan-Meier analysis was performed to evaluate outcome at follow-up.
Results:
Twenty-one patients did not undergo surgery, which left 133 patients as the study group. Atrial fibrillation was present in 45 of 133 patients. The interquartile range of the Agatston coronary calcium score was 0-471. Coronary CT angiography was diagnostic in 108 of 133 patients. Of these, 93 of 108 had no significant CAD (≤ 50% stenosis), and noncoronary cardiovascular surgery was performed in them without preoperative ICA. No patients in this group had postoperative ischemic events at follow-up. Coronary CT angiography was nondiagnostic in 25 of 133 patients who were referred for preoperative ICA. Multivariate analysis showed Agatston score to be the only independent predictor of nondiagnostic coronary CT angiography (odds ratio = 1.002; 95% confidence interval: 1.001, 1.003; P = .001). The best Agatston score cutoff for diagnostic coronary CT angiography was 579.
Conclusion:
In nonselected patients scheduled to undergo noncoronary cardiovascular surgery, preoperative coronary CT angiography was diagnostic in 81% of cases. Preoperative ICA could be safely avoided in patients without significant CAD by using coronary CT angiography. The Agatston score, but not the presence of atrial fibrillation, was an independent predictor of nondiagnostic coronary CT angiography.
Supplemental Material:
http://radiology.rsna.org/lookup/suppl/doi:10.1148/radiol.10100384/-/DC1.
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