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Related Concept Videos

Acne Infection01:27

Acne Infection

Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...
Changes in Skin Color: Clinical Perspectives01:14

Changes in Skin Color: Clinical Perspectives

The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
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Teratogenicity01:07

Teratogenicity

The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Clinical Applications of Epidermal Stem Cells01:19

Clinical Applications of Epidermal Stem Cells

Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own EpiSCs...
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Inhaled corticosteroids (ICS) are anti-inflammatory drugs used primarily in treating persistent asthma and providing long-term maintenance. They target the bronchial mucosa, the lining of the airways, to control inflammation, a critical factor in asthma progression and exacerbation.
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The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
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Published on: July 11, 2013

[Dermatologic therapy in pregnancy].

J Wohlrab1

  • 1Universitätsklinik und Poliklinik für Dermatologie und Venerologie, Martin Luther Universität Halle-Wittenberg, Ernst-Kromayer-Str. 5, 06097, Halle. johannes.wohlrab@medizin.uni-halle.de

Der Hautarzt; Zeitschrift Fur Dermatologie, Venerologie, Und Verwandte Gebiete
|November 17, 2010
PubMed
Summary
This summary is machine-generated.

Treating pregnant patients with medications demands careful consideration of risks and benefits. This guide aids dermatologists in selecting safe pharmacologic therapies for expectant mothers and their infants.

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Last Updated: Jun 6, 2026

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Area of Science:

  • Dermatology
  • Pharmacology
  • Teratology

Context:

  • Managing dermatological conditions during pregnancy presents unique challenges.
  • Balancing maternal and fetal well-being is paramount when prescribing medications.
  • Off-label drug use requires stringent precautions and documentation.

Purpose:

  • To provide a framework for benefit-risk assessment of dermatologic medications in pregnancy.
  • To evaluate the teratogenic potential of commonly used dermatologic drugs.
  • To offer practical recommendations for treating frequent dermatological indications in pregnant patients.

Summary:

  • Careful selection of pharmacologic agents, dosage, and administration is crucial for pregnant patients.
  • Teratogenic risk versus therapeutic benefit for both mother and child must be meticulously weighed.
  • The article reviews general aspects of benefit-risk evaluation and teratogenic potency of dermatologic medications.

Impact:

  • Empowers clinicians to make informed therapeutic decisions for pregnant patients.
  • Enhances patient safety by minimizing potential harm from pharmacologic interventions.
  • Provides resources for managing complex dermatological cases during pregnancy.