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Updated: Jun 6, 2026
06:18
A Bedside, Single Burr Hole Approach to Multimodality Monitoring in Severe Brain Injury
Published on: March 26, 2019
[Heart-brain interaction in intensive care medicine]
1Neurologische Klinik und Poliklinik, Klinikum der Universität München. klaus.jahn@med.uni-muenchen.de
Deutsche Medizinische Wochenschrift (1946)
|November 18, 2010
Summary
Neurological disorders can cause heart problems due to central adrenergic system activation. Treating the brain condition is key to improving cardiac symptoms and prognosis.
Area of Science:
- Neuroscience
- Cardiology
- Neurology
Background:
- Cardial diseases are frequent causes of neurological emergencies.
- Acute neurological disorders often present with systemic abnormalities, including cardial and pulmonary complications.
- This review specifically examines the cardiac consequences stemming from cerebral lesions.
Purpose of the Study:
- To review the cardial consequences of cerebral lesions.
- To highlight the role of the central adrenergic system in the pathophysiology of neurocardiac disorders.
- To discuss the implications for treatment and future research.
Main Methods:
- Literature review focused on cardial complications of neurological disorders.
- Analysis of the pathophysiological role of the adrenergic system.
- Synthesis of current understanding of neurocardiac disorders.
Main Results:
- Central adrenergic system activation is a key factor in the cardiac effects of brain disorders, regardless of etiology.
- Adrenergic stimulation can lead to ECG changes, elevated cardiac enzymes, arrhythmias, and sudden cardiac death.
- Cardial disorders like apical ballooning cardiomyopathy and neurogenic pulmonary edema can have a favorable prognosis with adequate neurological treatment.
Conclusions:
- The central adrenergic system significantly influences cardiac function following cerebral lesions.
- Effective management of the primary neurological disorder is crucial for resolving associated cardiac issues.
- Further research requires classifying neurocardiac disorders based on shared pathophysiology for improved treatment strategies.
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