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Related Concept Videos

Increased Body Temperature01:25

Increased Body Temperature

A body temperature above  38°C  (100.4 °F) is known as fever or pyrexia, and a person with fever is termed 'febrile.' Typically, the hypothalamus, a part of the brain that acts as the body's thermostat, regulates body temperature through a thermoregulatory setpoint. It receives signals from cold and warm thermal receptors throughout the body and adjusts the body's temperature accordingly. Fever occurs when this hypothalamic setpoint is altered, usually in response to an infection or illness.
Types of Fever01:25

Types of Fever

Fever can be triggered by several factors, including infections, nervous system disorders, certain cancers, blood diseases like leukemia, embolism, thrombosis, heatstroke, dehydration, surgical trauma, crushing injuries, and allergic reactions.
Here are the different types of fever:
Factors Affecting the Risk of Infection01:26

Factors Affecting the Risk of Infection

The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin create...
Methods of reducing fever01:22

Methods of reducing fever

The signs and symptoms of fever include hot and dry skin, flushed face, thirst, muscle aches, anorexia, headache, tachycardia, tachypnea, and fatigue. Elevated body temperature is reduced using two methods: pharmacological and nonpharmacological. Proper identification and treatment of the root cause of a fever is of utmost importance.
Pharmacological Methods of Reducing Fever:
Patterns of Fever01:26

Patterns of Fever

Before understanding the types and patterns of fever, it is essential to know its phases.
Stages of Infection01:26

Stages of Infection

Stages of infection describe what happens to a susceptible host once a pathogen invades the human body. The stages of infection are incubation, prodromal, illness, stage of decline, and convalescence. The incubation stage is the period from exposure to a pathogen until symptoms start. The infected person is unaware of impending illness as the pathogens grow and multiply within the body. The duration may vary depending on the type of infection. The incubation period of measles averages ten to...

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Related Experiment Video

Updated: Jun 6, 2026

Using a Bacterial Pathogen to Probe for Cellular and Organismic-level Host Responses
08:38

Using a Bacterial Pathogen to Probe for Cellular and Organismic-level Host Responses

Published on: February 22, 2019

[An immunocompromised host with a fever].

Carlijn D M Witjes1, Geert Kazemier

  • 1Erasmus Medisch Centrum, Rotterdam, afd. Heelkunde, Hepatobiliaire en Transplantatie Chirurgie, The Netherlands.

Nederlands Tijdschrift Voor Geneeskunde
|November 19, 2010
PubMed
Summary

A liver transplant patient with hepatocellular carcinoma developed a serious Aspergillus pneumonia due to a weakened immune system. This complication led to sepsis and multiple organ failure, ultimately resulting in the patient's death.

Area of Science:

  • Hepatology
  • Transplant Surgery
  • Infectious Diseases

Background:

  • Hepatocellular carcinoma (HCC) is a primary liver cancer.
  • Liver transplantation is a critical treatment option for advanced HCC.
  • Patients undergoing liver transplantation often have compromised immune systems, increasing infection risk.

Observation:

  • A 61-year-old female patient with HCC underwent liver transplantation.
  • Post-transplant, the patient developed Aspergillus pneumonia.
  • The patient presented with a compromised immune status.

Findings:

  • Aspergillus pneumonia is a severe opportunistic infection in immunocompromised patients.
  • Sepsis and multiple organ failure are life-threatening complications following invasive procedures.

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A Contemporary Warming/Restraining Device for Efficient Tail Vein Injections in a Murine Fungal Sepsis Model

Published on: November 6, 2020

Related Experiment Videos

Last Updated: Jun 6, 2026

Using a Bacterial Pathogen to Probe for Cellular and Organismic-level Host Responses
08:38

Using a Bacterial Pathogen to Probe for Cellular and Organismic-level Host Responses

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A Contemporary Warming/Restraining Device for Efficient Tail Vein Injections in a Murine Fungal Sepsis Model
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A Contemporary Warming/Restraining Device for Efficient Tail Vein Injections in a Murine Fungal Sepsis Model

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  • Invasive fungal infections can rapidly progress in transplant recipients.

    • Implications:

    • Highlight the critical need for vigilant monitoring of infections in liver transplant recipients.
    • Emphasize the importance of early diagnosis and management of invasive fungal infections.
    • Underscore the risks associated with compromised immunity post-liver transplantation.