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Updated: Jun 6, 2026

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Published on: June 6, 2025
CO2 laser improves 45S5 bioglass interaction with dentin
A S Bakry1, H Takahashi, M Otsuki
1Cariology and Operative Dentistry, Department of Restorative Sciences, Graduate School, Tokyo Medical and Dental University, 1-5-45, Yushima, Bunkyo-ku, Tokyo 113-8549, Japan. drahmedbakry@gmail.com.
Abstract:
Bioglass 45S5 is a bioactive glass that can create a layer of calcium-phosphate crystals on mineralized hard tissues. In this study, 45S5 bioglass was mixed with phosphoric acid and irradiated with CO(2) laser and examined as a possible aid in the treatment of dentin hypersensitivity. The dentinal surface modified by the aforementioned technique was chemically and micro-morphologically examined with a field emission scanning electron microscope (FE-SEM) equipped with an energy-dispersive x-ray spectroscope (EDS), and the crystalline structures of the examined dentinal surfaces were examined by x-ray diffraction (XRD). Moreover, the mechanical properties of the newly formed layer were examined by nanoindentation. The results showed that 45S5 bioglass could occlude the dentinal tubule orifices with calcium-phosphate crystals. The application of CO(2) laser potentially improved the mechanical organization of these crystals.
