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Updated: Jun 6, 2026

Identification of OTX1 and OTX2 As Two Possible Molecular Markers for Sinonasal Carcinomas and Olfactory Neuroblastomas
Published on: February 28, 2019
Nasal cavity ossifying fibrosarcoma: an unusual fibro-osseous neoplasm
Yadiel A Alameda1, Carlos Perez-Mitchell, José M Busquets
1Department of Otolaryngology-Head and Neck Surgery, Medical Sciences Campus, PO Box 365067, San Juan 00936-5067, Puerto Rico. yaye7@yahoo.com
Abstract:
We describe the case of a 65-year-old woman who presented with left nasal obstruction. Clinical and radiographic examinations revealed the presence of a soft-tissue mass that had obliterated the left nasal cavity. The mass was completely excised via an endoscopic approach. Histopathologic examination identified the tumor as an ossifying fibrosarcoma. The patient recovered uneventfully and remained free of disease at the 2-year postoperative follow-up. To the best of our knowledge, no case of an ossifying fibrosarcoma of the nasal cavity has been previously reported in the English-language literature. We discuss the features of this case and the clinical presentation, diagnosis, and management of fibrosarcomas of the nasal cavity and paranasal sinuses.
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