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Related Concept Videos

Bone Disorders01:29

Bone Disorders

Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Compact Bone01:27

Compact Bone

Most bones contain compact and spongy osseous tissue, but their distribution and concentration vary based on the bone's overall function.
Compact bone, also called cortical bone, is the denser, stronger of the two types of bone tissue. It is found under the periosteum and in the diaphyses of long bones, where it provides support and protection. The microscopic structural unit of compact bone is called an osteon, or haversian system. Each osteon is composed of concentric rings of calcified...
Fractures: Bone Repair01:27

Fractures: Bone Repair

Treatment for a fracture is based on the type of break, the bone affected, and the patient's age.
Minor fractures with no bone displacement are treated by immobilizing the fractured bone using a cast or splint. However, in the case of fractures with displaced bones, the broken bones are repositioned before immobilization to ensure successful healing without deformation and loss of function. The realignment of fractured bone ends is performed through a process called reduction. If the procedure...
Aneurysm I: Introduction01:30

Aneurysm I: Introduction

An aortic aneurysm is a localized outpouching or dilation at a weak point in the artery wall. It may involve different parts of the aorta, such as the abdominal aorta, aortic arch, or thoracic aorta.Etiological factorsSeveral disorders are associated with aortic aneurysms.Congenital causes, such as primary connective tissue disorders like Marfan syndrome, impact the integrity and strength of connective tissues, notably affecting the aorta. Marfan syndrome is a genetic disorder that specifically...
Bone Formation by Intramembranous Ossification01:29

Bone Formation by Intramembranous Ossification

Intramembranous ossification is one of the two processes involved in the development of bones within an embryo. The flat bones of the face, most of the cranial bones, and the clavicles are formed via this process. During intramembranous ossification, the bones develop directly from sheets of undifferentiated mesenchymal connective tissue.
The process begins when mesenchymal cells in the embryonic skeleton gather together and differentiate into osteogenic cells, which then develop into...
Gross Anatomy of Bone01:17

Gross Anatomy of Bone

The two main features of a long bone are the diaphysis and the epiphysis.
The diaphysis is the tubular shaft that runs between the proximal and distal ends of the bone. The walls of the diaphysis are composed of dense and hard compact bone made of numerous osteons — the functional unit of the compact bone. The hollow region in the diaphysis is called the medullary cavity, which harbors the bone marrow. In infants and children, this marrow cavity is filled with red marrow, whereas in adults, it...

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Related Experiment Video

Updated: Jun 6, 2026

Intrathecal Application of a Fluorescent Dye for the Identification of Cerebrospinal Fluid Leaks in Cochlear Malformation
06:59

Intrathecal Application of a Fluorescent Dye for the Identification of Cerebrospinal Fluid Leaks in Cochlear Malformation

Published on: February 29, 2020

[Aneurysmal bone cyst in children].

L A Semenova, O A Malakhov, K V Zherdev

    Arkhiv Patologii
    |November 20, 2010
    PubMed
    Summary

    Aneurysmal bone cysts (ABC) are destructive bone lesions often seen in young individuals. Surgical treatment is standard, but high recurrence rates necessitate careful consideration of patient and cyst factors.

    Area of Science:

    • Orthopedic Oncology
    • Skeletal Pathology

    Background:

    • Aneurysmal bone cyst (ABC) is a destructive, blood-filled lesion of bone.
    • Characterized by cavities, connective tissue septa, and high intraosseous pressure.
    • Most common in the second decade of life, often in the metaphyseal region of long bones.

    Discussion:

    • Surgery is the primary treatment modality for ABC.
    • Recurrence rates are significant and influenced by surgical technique and patient risk factors.
    • Risk stratification involves age, cyst size, disease phase, and anatomical location.

    Key Insights:

    • ABC presents as a tumor-like destructive lesion with characteristic vascular cavities.
    • High intraosseous pressure is a hallmark of ABC.
    • Adolescents and young adults are the most affected demographic.

    Related Experiment Videos

    Last Updated: Jun 6, 2026

    Intrathecal Application of a Fluorescent Dye for the Identification of Cerebrospinal Fluid Leaks in Cochlear Malformation
    06:59

    Intrathecal Application of a Fluorescent Dye for the Identification of Cerebrospinal Fluid Leaks in Cochlear Malformation

    Published on: February 29, 2020

    Outlook:

    • Further research into risk factors influencing ABC recurrence is warranted.
    • Optimizing surgical strategies and risk stratification may improve patient outcomes.
    • Understanding the pathogenesis of ABC could lead to novel therapeutic approaches.