Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Potentiometry: Membrane Electrodes01:15

Potentiometry: Membrane Electrodes

Membrane electrodes, also known as p-ion electrodes, use membranes that selectively interact with free analyte ions, generating a potential difference across the membrane. The resulting membrane potential, known as the asymmetry potential, is not zero even when analyte concentrations on both sides of the membrane are equal. The membrane's response is typically not selective to a single analyte but proportional to the concentration of all ions in the sample solution capable of interacting at the...
The Electrical Double Layer01:30

The Electrical Double Layer

In the region where two bulk phases meet, an intricate electric charge distribution arises due to charge transfer, ion adsorption, molecular orientation, and charge distortion. This complex distribution is commonly referred to as the electrical double layer.When a solid electrode interfaces with ions in an electrolyte solution, the speed of electron transfer dictates the rates of oxidation and reduction. The electrode acquires a charge through the escape of atoms into the solution as cations or...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Electrical discrimination of lysine methylation states at the single-molecule level.

Analytical sciences : the international journal of the Japan Society for Analytical Chemistry·2026
Same author

Nanofluidic systems for ionic intelligence.

Nanoscale horizons·2026
Same author

Three-dimensional plasmonic nanopores for DNA-PAINT and dual-material Au/Si architectures.

Journal of nanobiotechnology·2026
Same author

Single-molecule detection of amino acid phosphorylation using electron tunnelling currents: toward neurodegenerative disease diagnosis.

Nanoscale·2026
Same author

Chemistry-driven autonomous nanopore membranes.

Nature communications·2026
Same author

Beyond ensemble averages: single-entity approaches for complex systems.

Analytical sciences : the international journal of the Japan Society for Analytical Chemistry·2026

Related Experiment Video

Updated: Jun 6, 2026

Antifouling Self-assembled Monolayers on Microelectrodes for Patterning Biomolecules
10:27

Antifouling Self-assembled Monolayers on Microelectrodes for Patterning Biomolecules

Published on: August 25, 2009

Molecule-electrode bonding design for high single-molecule conductance.

Kazumichi Yokota1, Masateru Taniguchi, Makusu Tsutsui

  • 1The Institute of Scientific and Industrial Research, Osaka University, 8-1 Ibaraki, Osaka 567-0047, Japan.

Journal of the American Chemical Society
|November 20, 2010
PubMed
Summary

We enhanced single-molecule conductance using dithiol and diselenol terthiophenes. Replacing sulfur with selenium in molecule-electrode bonds significantly boosted conductance, showing promise for future organic electronics.

More Related Videos

A Microfluidic-based Electrochemical Biochip for Label-free DNA Hybridization Analysis
14:53

A Microfluidic-based Electrochemical Biochip for Label-free DNA Hybridization Analysis

Published on: September 10, 2014

Multi-analyte Biochip (MAB) Based on All-solid-state Ion-selective Electrodes (ASSISE) for Physiological Research
08:03

Multi-analyte Biochip (MAB) Based on All-solid-state Ion-selective Electrodes (ASSISE) for Physiological Research

Published on: April 18, 2013

Related Experiment Videos

Last Updated: Jun 6, 2026

Antifouling Self-assembled Monolayers on Microelectrodes for Patterning Biomolecules
10:27

Antifouling Self-assembled Monolayers on Microelectrodes for Patterning Biomolecules

Published on: August 25, 2009

A Microfluidic-based Electrochemical Biochip for Label-free DNA Hybridization Analysis
14:53

A Microfluidic-based Electrochemical Biochip for Label-free DNA Hybridization Analysis

Published on: September 10, 2014

Multi-analyte Biochip (MAB) Based on All-solid-state Ion-selective Electrodes (ASSISE) for Physiological Research
08:03

Multi-analyte Biochip (MAB) Based on All-solid-state Ion-selective Electrodes (ASSISE) for Physiological Research

Published on: April 18, 2013

Area of Science:

  • Molecular electronics
  • Organic conductors
  • Materials science

Background:

  • High conductance in organic materials is crucial for advanced electronics.
  • Molecule-electrode interfaces significantly impact single-molecule conductance.
  • Thiophene-based molecules are promising candidates for organic conductors.

Purpose of the Study:

  • To investigate the effect of sulfur (S) versus selenium (Se) in molecule-electrode bonds on single-molecule conductance.
  • To apply intermolecular interaction design principles to molecule-electrode interfaces for enhanced conductance.
  • To explore dithiol and diselenol terthiophenes for high single-molecule conductance applications.

Main Methods:

  • Fabrication and characterization of single-molecule junctions using dithiol and diselenol terthiophenes.
  • Utilizing gold-sulfur (Au-S) and gold-selenium (Au-Se) bonds for molecule-electrode connections.
  • Conductance measurements of single-molecule junctions.

Main Results:

  • Dithiol and diselenol single-molecule junctions exhibited the highest conductance among tested Au-S and Au-Se bonded junctions.
  • Diselenol single-molecule junctions demonstrated superior conductance compared to dithiol counterparts.
  • The study confirmed that replacing sulfur with selenium atoms in molecule-electrode bonds is an effective strategy for increasing single-molecule conductance.

Conclusions:

  • Replacing sulfur with selenium atoms in molecule-electrode bonds is a highly effective strategy for achieving high single-molecule conductance.
  • Dithiol and diselenol terthiophenes serve as excellent molecular building blocks for high-performance organic conductors.
  • This research provides a key design principle for optimizing molecular junctions in organic electronics.