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Updated: Jun 6, 2026

Simultaneous Assessment of Cardiomyocyte DNA Synthesis and Ploidy: A Method to Assist Quantification of Cardiomyocyte Regeneration and Turnover
08:03

Simultaneous Assessment of Cardiomyocyte DNA Synthesis and Ploidy: A Method to Assist Quantification of Cardiomyocyte Regeneration and Turnover

Published on: May 23, 2016

Myocyte turnover in the aging human heart.

Jan Kajstura1, Narasimman Gurusamy, Barbara Ogórek

  • 1Department of Anesthesia and Medicine and Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA. jkajstura@partners.org

Circulation Research
|November 20, 2010
PubMed
Summary

The aging female heart shows superior cardiomyocyte regeneration compared to males, with human cardiac stem cells (hCSCs) playing a key role in maintaining cardiac health and slowing aging.

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