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Related Concept Videos

Probiotics01:22

Probiotics

Probiotics are live, non-pathogenic microorganisms that confer health benefits by modulating the gut microbiota. The human gastrointestinal tract harbors a complex microbial ecosystem, and the balance of this microbiota is crucial for digestive and systemic health. Among the most extensively studied and utilized probiotics are species formerly classified within the genera Lactobacillus and Bifidobacterium. These organisms not only naturally colonize the human gut but are also consumed through...
Microbiota Modulation by Antibiotics01:21

Microbiota Modulation by Antibiotics

Antibiotics have revolutionized modern medicine by saving countless lives from bacterial infections. However, their widespread use has inadvertently harmed the delicate balance of the human gut microbiota. The gut microbiota, a complex community of bacteria, archaea, viruses, and fungi, plays a vital role in regulating metabolism, immune responses, and maintaining intestinal health. Antibiotics, especially broad-spectrum types, disrupt this ecosystem by eradicating both harmful and beneficial...
Development of Human Microbiota01:30

Development of Human Microbiota

The human microbiota begins developing at birth and undergoes continual change as we age. Infancy marks a critical period of microbial sensitivity, offering a “window of opportunity” during which beneficial microbes help mature the immune system. By age three, children typically develop a more stable and diverse microbial community. Newborns acquire microbes from their immediate environment; vaginal delivery favors maternal vaginal microbes, while cesarean births favor microbes from the skin...
Microbes in the Production of Fermented Foods01:27

Microbes in the Production of Fermented Foods

Lactic acid bacteria (LAB) and molds are instrumental in fermenting plant-based foods to enhance preservation and ensure year-round availability. These microbial processes convert plant carbohydrates into organic acids and other metabolites that inhibit spoilage organisms and contribute to the sensory qualities of the final product.In sauerkraut production, cabbage goes through a microbial succession that starts with cocci such as Leuconostoc mesenteroides. These microbes begin fermentation by...
Dysbiosis of the Gut Microbiota01:18

Dysbiosis of the Gut Microbiota

The human gut microbiome includes a diverse array of microbial species, including beneficial commensals and opportunistic pathogens, which interact to support host health. These microbes contribute to essential functions such as nutrient metabolism, immune system modulation, and maintenance of intestinal barrier integrity. However, disruptions to this equilibrium—referred to as dysbiosis—can have widespread physiological consequences.Dysbiosis is often characterized by reduced microbial...
Rapid Identification of Pathogens01:25

Rapid Identification of Pathogens

MALDI-TOF MS has transformed clinical microbiology by offering a rapid and reliable method for pathogen identification. The traditional approach to microbial identification typically involves time-consuming culture techniques and biochemical tests, which can delay the initiation of appropriate antimicrobial therapy. MALDI-TOF MS avoids these delays by using characteristic ribosomal protein mass patterns of microbial cells, enabling accurate species-level identification within minutes.Principle...

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Related Experiment Video

Updated: Jun 6, 2026

Probiotic Studies in Neonatal Mice Using Gavage
10:36

Probiotic Studies in Neonatal Mice Using Gavage

Published on: January 27, 2019

Too fast, too soon to call it "probiotic".

V L Miniello1, A Colasanto, L Diaferio

  • 1Clinica Pediatrica Salvatore Maggiore, Dipartimento di Biomedicina dell'Età Evolutiva, Università degli Studi di Bari.

Minerva Pediatrica
|November 25, 2010
PubMed
Summary

Probiotics, live microorganisms conferring health benefits, show promise in pediatric conditions like diarrhea and atopic diseases. Strain specificity is crucial, necessitating standardized assessment methods for efficacy and safety.

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Novel Production Protocol for Small-scale Manufacture of Probiotic Fermented Foods
08:38

Novel Production Protocol for Small-scale Manufacture of Probiotic Fermented Foods

Published on: September 10, 2016

Related Experiment Videos

Last Updated: Jun 6, 2026

Probiotic Studies in Neonatal Mice Using Gavage
10:36

Probiotic Studies in Neonatal Mice Using Gavage

Published on: January 27, 2019

Novel Production Protocol for Small-scale Manufacture of Probiotic Fermented Foods
08:38

Novel Production Protocol for Small-scale Manufacture of Probiotic Fermented Foods

Published on: September 10, 2016

Area of Science:

  • Microbiology
  • Pediatric Gastroenterology
  • Nutritional Science

Background:

  • Probiotics are live microorganisms providing health benefits to the host.
  • Defined by FAO/WHO, their pediatric applications include diarrhea, atopic diseases, and inflammatory bowel conditions.
  • Strain specificity necessitates careful evaluation, as pooled data can be misleading.

Purpose of the Study:

  • To review the definition and established benefits of probiotics.
  • To highlight the need for standardized methodologies in assessing probiotic efficacy and safety.
  • To discuss international criteria for probiotic evaluation.

Main Methods:

  • Review of FAO/WHO reports and scientific literature.
  • Analysis of international criteria for probiotic assessment.
  • Consideration of recent EFSA guidelines on health claim submissions.

Main Results:

  • Probiotics demonstrate efficacy in pediatric diarrhea and potential in atopic and inflammatory conditions.
  • Strain-specific effects are evident, emphasizing the need for individualized assessment.
  • International criteria and naming protocols are essential for consistent evaluation.

Conclusions:

  • Standardized methodologies are critical for evaluating probiotic efficacy and safety.
  • Strain identification, naming, and product consistency are key for health claims.
  • Further research and consensus on assessment are needed for reliable probiotic application.