Related Experiment Video
Updated: Jun 6, 2026

Improved Registration of 3D CT Angiography with X-ray Fluoroscopy for Image Fusion During Transcatheter Aortic Valve Implantation
Published on: June 3, 2018
Endovascular image-guided navigation: validation of two volume-volume registration algorithms
Frode Manstad-Hulaas1, Geir Arne Tangen, Stefanie Demirci
1Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim. frode.manstad.hulaas@ntnu.no
Accurate registration of preoperative to intraoperative CT scans is crucial for endovascular navigation. The CAMP algorithm demonstrated superior accuracy compared to the Siemens algorithm in this study.
Area of Science:
- Medical Imaging
- Surgical Navigation
- Computational Anatomy
Background:
- Intraoperative CT scans have limited volume, hindering navigation system use.
- Preoperative CT scans offer larger volume coverage, essential for comprehensive navigation.
- Accurate registration between preoperative and intraoperative CT is vital for endovascular navigation.
Purpose of the Study:
- To evaluate the accuracy of two volume-volume registration algorithms (Siemens and CAMP) for endovascular navigation.
- To compare the performance of Siemens and CAMP algorithms against reference registrations.
Main Methods:
- Two volume-volume registration algorithms (Siemens, CAMP) were assessed.
- Fourteen intra- and postoperative CT datasets from abdominal aortic aneurysm patients were used.
- Registration accuracy was evaluated using five landmarks and calculating root mean square distances, with rigid body registration as reference.
Main Results:
- CAMP algorithm achieved a mean accuracy of 4.02 ± 1.52 mm.
- Siemens algorithm achieved a mean accuracy of 5.05 ± 4.74 mm.
- Reference registrations showed the highest accuracy at 2.72 ± 1.18 mm, with significant differences between algorithms (p < 0.001).
Conclusions:
- The CAMP algorithm offers more accurate registration than the Siemens algorithm for endovascular navigation.
- Both evaluated algorithms show potential for improving image guidance in endovascular procedures.
- Further refinement of registration algorithms is needed to match the accuracy of reference methods.
Related Concept Videos
Imaging Studies VII: Vascular Imaging
Radiological Investigation II: MRI and Ventilation Perfusion Scan
Magnetic Resonance Imaging (MRI) and Ventilation Perfusion Scans are two radiological investigations that offer detailed diagnostic images of the body, particularly lung structures.
MRI
MRI uses magnetic fields and radiofrequency signals to distinguish between normal and abnormal tissues. This technology provides a more detailed diagnostic image than CT scans, enabling it to characterize pulmonary nodules, stage bronchogenic carcinoma, and evaluate inflammatory activity in...

