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Bipolar affective disorder, type II, apparently precipitated by donepezil
Chris Collins1, Bronwyn Copeland, Matthew Croucher
1Princess Margaret Hospital, Christchurch, New Zealand. chris.collins@cdhb.govt.nz
International Psychogeriatrics
|November 25, 2010
Summary
Pro-cholinergic agents can cause depression, but rare cases show mood elevation. This study details a novel instance of mood elevation in a patient without prior psychiatric conditions.
Area of Science:
- Neuroscience
- Psychiatry
- Pharmacology
Background:
- Pro-cholinergic agents are known to induce depressed mood.
- Case reports suggest a rare link between cholinesterase inhibitors and mood elevation in specific patient groups.
Observation:
- This report describes a unique case of mood elevation.
- The patient had no pre-existing major functional psychiatric disorders or organic disorders.
Findings:
- A patient experienced mood elevation while on pro-cholinergic agents.
- This contrasts with the typical depressive effects observed with such agents.
Implications:
- This case expands the understanding of pro-cholinergic agent effects on mood.
- Further research may explore the mechanisms behind mood elevation in specific contexts.
- Highlights the need for individualized patient monitoring regarding psychiatric side effects.
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