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Related Concept Videos

Assessment of the Mouth01:26

Assessment of the Mouth

A thorough mouth assessment, including inspection and palpation of the lips, gums, tongue, tonsils, uvula, and pharynx, is crucial in detecting potential health issues. Diseases ranging from oral cancer to systemic conditions like diabetes could be identified early through careful oral examination. This article provides a detailed guide on conducting a comprehensive mouth assessment.
Mouth Inspection
The inspection begins with visually examining the mouth for symmetry, color, and size.
Herpes01:28

Herpes

Herpes simplex type 1 (HSV‑1) is a widespread pathogen responsible for orolabial lesions. It is an enveloped, double-stranded DNA (dsDNA) virus belonging to the family Herpesviridae. Once the virus infects a host cell, its double‑stranded DNA genome is delivered into the nucleus, where a coordinated cascade of immediate‑early, early, and late gene expression directs viral DNA replication, structural protein synthesis, and virion assembly. After primary infection of epithelial cells, HSV-1...
Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Oral Cavity01:11

Oral Cavity

The oral cavity, or the mouth, is a complex structure in humans that plays a vital role in our day-to-day lives. Its role is not only in chewing and swallowing food; it also plays a role in speech and facial expressions.
Teeth: The teeth are the hardest structures in our bodies. Humans have two sets of teeth throughout their lifetime: deciduous (baby) teeth and permanent teeth. Each tooth consists of several parts: the crown (visible part), the root (embedded in the jaw), enamel (hard outer...

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Examination of Oral Candida Infection in Primary Sjögren's Syndrome Patients
05:26

Examination of Oral Candida Infection in Primary Sjögren's Syndrome Patients

Published on: March 1, 2024

Oral lichen planus.

Pallavi Parashar1

  • 1Department of Diagnostic and Biological Sciences, University of Colorado Denver School of Dental Medicine, Aurora, CO 80045, USA. pallavi.parashar@ucdenver.edu

Otolaryngologic Clinics of North America
|November 25, 2010
PubMed
Summary
This summary is machine-generated.

Oral lichen planus (OLP) is a chronic immune condition affecting middle-aged women, with an obscure cause. Diagnosis requires strict criteria, and while OLP is premalignant, the cancer risk appears low.

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Area of Science:

  • Oral medicine
  • Immunodermatology
  • Oncology

Background:

  • Oral lichen planus (OLP) is a chronic, immune-mediated condition.
  • It predominantly affects middle-aged women, but its etiology is largely unknown.
  • Accurate diagnosis is crucial to differentiate OLP from similar oral lesions.

Purpose of the Study:

  • To define the diagnostic criteria for OLP.
  • To assess the premalignant potential of OLP.
  • To evaluate the risk of neoplastic transformation in OLP patients.

Main Methods:

  • Review of clinical and histological diagnostic criteria for OLP.
  • Analysis of existing literature on OLP etiology and management.
  • Evaluation of reported cases of malignant transformation in OLP.

Main Results:

  • Diagnosis of OLP necessitates stringent clinical and histological evaluation.
  • Differential diagnosis is essential to exclude mimicking conditions.
  • The risk of malignant transformation associated with OLP is considered low.

Conclusions:

  • OLP diagnosis requires rigorous adherence to established criteria.
  • While OLP carries a premalignant potential, the neoplastic risk is minimal.
  • Further research into OLP pathogenesis may improve understanding and management.