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Related Experiment Video

Updated: Jun 6, 2026

Microelectrode Guided Implantation of Electrodes into the Subthalamic Nucleus of Rats for Long-term Deep Brain Stimulation
10:52

Microelectrode Guided Implantation of Electrodes into the Subthalamic Nucleus of Rats for Long-term Deep Brain Stimulation

Published on: October 2, 2015

Towards a Switched-Capacitor based Stimulator for efficient deep-brain stimulation.

Jose Vidal1, Maysam Ghovanloo

  • 1Electrical and Computer Engineering Department, Georgia Institute of Technology, Atlanta, GA 30308, USA. jose.vidal@gatech.edu

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
|November 25, 2010
PubMed
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A new switched-capacitor stimulator (SCS) offers efficient and safe neurological stimulation for devices like those used in Deep Brain Stimulation (DBS). This prototype provides precise control over stimulation parameters, enhancing safety and functionality for implantable neurological stimulators (INS).

Area of Science:

  • Biomedical Engineering
  • Neuroscience
  • Electrical Engineering

Background:

  • Implantable neurological stimulators (INS) require precise and safe electrical stimulation.
  • Conventional voltage-controlled stimulators (VCS) are efficient but lack precise current control.
  • Current-controlled stimulators (CCS) offer safety and control but can be less power-efficient.

Purpose of the Study:

  • To develop and evaluate a novel 4-channel switched-capacitor based stimulator (SCS) prototype.
  • To combine the efficiency of VCS with the safety and controllability of CCS.
  • To assess the feasibility and functionality of the SCS for Deep Brain Stimulation (DBS).

Main Methods:

  • Developed a discrete 4-channel switched-capacitor based stimulator (SCS) prototype.

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Last Updated: Jun 6, 2026

Microelectrode Guided Implantation of Electrodes into the Subthalamic Nucleus of Rats for Long-term Deep Brain Stimulation
10:52

Microelectrode Guided Implantation of Electrodes into the Subthalamic Nucleus of Rats for Long-term Deep Brain Stimulation

Published on: October 2, 2015

Targeting Neuronal Fiber Tracts for Deep Brain Stimulation Therapy Using Interactive, Patient-Specific Models
14:14

Targeting Neuronal Fiber Tracts for Deep Brain Stimulation Therapy Using Interactive, Patient-Specific Models

Published on: August 12, 2018

  • Integrated a LabVIEW graphical user interface (GUI) for parameter control (voltage, current, pulse width, frequency, channel).
  • Utilized a floating current sensor for charge-balanced biphasic stimulation and safety verification.
  • Analyzed performance using an electrode-electrolyte interface (EEI) model and pacing electrodes in saline.
  • Main Results:

    • The SCS prototype demonstrated fine control over key stimulation parameters.
    • Charge-balanced biphasic stimulation was achieved, ensuring safety.
    • The system successfully integrated hardware and software for user-friendly operation.
    • Initial analyses confirmed the feasibility of the SCS approach.

    Conclusions:

    • The novel switched-capacitor based stimulator (SCS) is a feasible and functional prototype.
    • This technology offers a promising approach for safe, effective, and power-efficient neurological stimulation.
    • The SCS has potential applications in Deep Brain Stimulation (DBS) and other implantable neurological stimulator (INS) systems.