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Updated: Jun 6, 2026

Using Three-color Single-molecule FRET to Study the Correlation of Protein Interactions
Published on: January 30, 2018
An information theory-based tool for characterizing the interaction environment of a protein
Raimon Massanet-Vila1, Joan-Josep Gallardo-Chacon, Pere Caminal
1Dept. ESAII, Technical University of Catalonia (UPC), Barcelona, Spain. raimon.massanet@upc.edu
Abstract:
In recent years large amounts of information have been accumulated in proteomic, genetic and metabolic databases. Much effort has been dedicated to developing methods that successfully exploit, organize and structure this information. However, there is no application, that we know of, that semantically characterizes the interaction environment in which a protein exists. A high-throughput software package has been developed to retrieve information from publicly available databases, such as the Gene Ontology Annotation (GOA) database and the Human Proteome Resource Database (HPRD) and structure their information. This information is presented to the user as groups of semantically described dense interaction subnetworks that interact with a target protein.
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