Long-Term Cyclophosphamide Treatment in a Case with Serpiginous Choroiditis

Area of Science:

• Ophthalmology
• Immunosuppressive therapy

Background:

• Serpiginous choroiditis is a rare, bilateral inflammatory eye disease.
• Limited treatment options exist, often with significant side effects.

Observation:

• A case of unilateral active serpiginous choroiditis was treated with oral cyclophosphamide.
• The treatment duration was 12 months.

Findings:

• Long-term cyclophosphamide therapy led to a positive response in the active lesion.
• No recurrences or significant systemic side effects were observed during the treatment period.

Implications:

• This case supports the efficacy of long-term cyclophosphamide for serpiginous choroiditis.
• Cyclophosphamide may be a viable treatment option for improving vision and preventing disease progression.