Related Experiment Video
Updated: Jun 6, 2026

A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products
Published on: October 4, 2019
Neojaponicone A, a bioactive sesquiterpene lactone dimer with an unprecedented carbon skeleton from Inula japonica
Jiang Jiang Qin1, Li Yan Wang, Jia Xian Zhu
1School of Pharmacy, Shanghai Jiao Tong University, Shanghai 200240, P. R. China.
Abstract:
Five new dimeric sesquiterpene lactones, neojaponicone A (1) and japonicones M-P (2-5) were isolated from the aerial part of Inula japonica. Neojaponicone A (1) has an unprecedented carbon skeleton with an unusual valerolactone system formed between a guaianolide and an eudesmane. The structure and absolute configuration of 1 were established by extensive analysis of spectroscopic data and computational approaches.
Related Concept Videos
Biosynthesis of Polysaccharides
Organic Compounds
Cellulose and Pectic Polysaccharides
As a cell matures, its cell wall specializes according to its type. For example, the parenchyma cells of...
Structure of Conjugated Dienes
Conjugated dienes are compounds characterized by the presence of alternating double and single bonds. In a conjugated system like 1,3-butadiene, the unhybridized 2p orbital on each carbon overlaps continuously, allowing the π electrons to be delocalized across the entire molecule. In contrast, this type of overlap does not occur in cumulated and isolated dienes, such as 2,3-pentadiene and 1,4-pentadiene, respectively. Instead, the π electrons remain localized between the double...
[4+2] Cycloaddition of Conjugated Dienes: Diels–Alder Reaction
Glycosaminoglycans
GAGS are found in the extracellular matrix of vertebrates, invertebrates, and bacteria. Due to their polar nature they attract water, and serve as excellent lubricants or shock absorbers in an animal body.
Hyaluronic...
