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Updated: Jun 6, 2026
06:04
Upper-extremity Approach for Secondary Access in Transfemoral Transcatheter Aortic Valve Implantation
Published on: August 8, 2025
[Transcatheter valve interventions for heart valve diseases]
1Klinik für Kardiologie und Angiologie, Medizinische Hochschule Hannover, Carl-Neuberg-Straße 1, Hannover, Germany. schaefer.arnd@mh-hannover.de
Der Internist
|November 25, 2010
Summary
Transcatheter aortic valve implantation and MitraClip® system offer effective treatment for high-risk patients with severe aortic stenosis and mitral regurgitation, respectively. Percutaneous pulmonary valve implantation is a less invasive alternative for congenital heart disease patients needing right ventricular outflow tract reconstruction.
Area of Science:
- Cardiovascular Medicine
- Interventional Cardiology
- Cardiac Surgery
Context:
- Severe aortic stenosis and mitral regurgitation are significant causes of morbidity and mortality, particularly in elderly and high-risk surgical patients.
- Transcatheter aortic valve implantation (TAVI) and MitraClip® system provide minimally invasive options for patients unsuitable for traditional surgery.
- Percutaneous pulmonary valve implantation (PPVI) addresses the need for right ventricular outflow tract reconstruction in adults with congenital heart disease.
Purpose:
- To review the current status and efficacy of transcatheter interventions for valvular heart disease.
- To highlight the role of TAVI in severe aortic stenosis, MitraClip® in mitral regurgitation, and PPVI in congenital heart disease.
- To emphasize the growing importance of percutaneous approaches as alternatives to conventional surgery.
Summary:
- Transcatheter aortic valve implantation (TAVI) demonstrates safety and efficacy in selected high-risk patients with severe aortic stenosis, though randomized trials are needed for broader application.
- The double orifice MitraClip® technique effectively reduces mitral regurgitation severity in both degenerative and functional etiologies for high-risk surgical candidates.
- Percutaneous pulmonary valve implantation (PPVI) has emerged as a valuable, less morbid alternative to repeated surgical interventions for right ventricular outflow tract reconstruction in adults with congenital heart disease.
Impact:
- Transcatheter therapies are expanding treatment options for valvular heart disease, improving outcomes for high-risk patient populations.
- These minimally invasive procedures reduce patient morbidity and may offer long-term benefits, potentially expanding indications to lower-risk patients.
- PPVI represents a significant advancement in managing complex congenital heart disease, avoiding the high morbidity associated with reoperations.
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