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Mycobacterium porcinum peritonitis in a patient on continuous ambulatory peritoneal dialysis
Ritesh Patil1, Trupti Patil, Louis Schenfeld
1Department of Internal Medicine, Temple University/Conemaugh Valley Memorial Medical Center, 1086 Franklin Street, Johnstown, PA 15905, USA. drriteshpatil@yahoo.co.in
Abstract:
Mycobacterium porcinum has been reported to cause a variety of illnesses including wound infections, respiratory tract infections, osteomyelitis and catheter-related bacteremias. We report the first case of M. porcinum peritonitis in a patient on continuous ambulatory peritoneal dialysis (CAPD). A 67-year-old woman on CAPD presented with three weeks of constitutional symptoms and abdominal pain. Peritoneal fluid cultures on day three grew acid-fast rods. Nocardiosis was suspected and the patient was empirically treated with amikacin and trimethoprim-sulfamethoxazole. The dialysis catheter was removed. Two weeks later final culture results revealed M. porcinum. Ciprofloxacin and trimethoprim-sulfamethoxazole were initiated with good clinical response.
Insights
This case report details the first instance of Mycobacterium porcinum peritonitis in a continuous ambulatory peritoneal dialysis (CAPD) patient. Early suspicion and targeted antibiotic therapy led to a successful clinical outcome.
Area of Science:
- Medical Microbiology
- Infectious Diseases
- Nephrology
Background:
- Mycobacterium porcinum is a known pathogen causing infections like wound, respiratory, osteomyelitis, and catheter-related bacteremia.
- Peritonitis is a serious complication for patients undergoing peritoneal dialysis.
Observation:
- A 67-year-old female on continuous ambulatory peritoneal dialysis (CAPD) presented with constitutional symptoms and abdominal pain.
- Peritoneal fluid cultures initially revealed acid-fast rods, leading to suspicion of Nocardia.
- Empirical treatment included amikacin and trimethoprim-sulfamethoxazole, with dialysis catheter removal.
Findings:
- Final culture results identified Mycobacterium porcinum as the causative agent.
- The patient showed a good clinical response after initiating ciprofloxacin and trimethoprim-sulfamethoxazole therapy.
Implications:
- This case highlights M. porcinum as a potential cause of peritonitis in CAPD patients.
- Prompt diagnosis and appropriate antibiotic selection are crucial for managing M. porcinum peritonitis.
- Further research may be needed to understand the epidemiology and optimal treatment strategies for this infection in dialysis patients.
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