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[Postoperative prognostic analysis of 96 patients with stage I non-small cell lung cancer]
1Department of Thoracic and Cardiovascular Surgery , The Third University Hospital and Surgery Research Institute of The Third Military Medical University , Chongqing 400042, P . R . China.
Background:
To compare the postoperative survival difference between stage IA and IB non-small cell lung cancer ( NSCLC) and analyze the prognostic factors affecting the long-term survival of resected stage I NSCLC.
Methods:
Ninety-six patients with stage I NSCLC surgically treated in our department from 1974 to 1995 were studied retrospectively. Nine possible prognostic factors including gender, age, T grade, primary tumor size, visceral pleural involvement , type of resection, pathological type, tumor differentiation, and location were analyzed by univariate analysis and multivariate analysis subsequently.
Results:
There was a significant difference in postoperative 5-year survival between stage IA and IB ( P < 0. 05) . The significant prognostic factors ( P < 0. 05) demonstrated by univariate analysis included T grade, primary tumor size, visceral pleural involvement and tumor differentiation, while visceral pleural involvement and tumor differentiation served as the independent prognostic factors ( P < 0. 05) with multivariate analysis.
Conclusions:
Stage I NSCLC should be subdivided into IA and IB whose five-year survival was proved to be significantly different. Visceral pleural involvement as well as tumor differentiation played as the independent prognostic factors in resected stage I NSCLC.
