Related Experiment Video
Updated: Jun 6, 2026

Glutamine Flux Imaging Using Genetically Encoded Sensors
Published on: July 31, 2014
Gaseotransmitters: new frontiers for translational science
1Department of Anesthesiology, The University of Texas Medical Branch, Galveston, TX 77555-1102, USA. szabocsaba@aol.com
Abstract:
Translational research on endogenous gaseous mediators--nitric oxide, carbon monoxide, and hydrogen sulfide--has exploded over the past decade. Drugs that modulate either the gaseous mediators themselves or their related intracellular signaling pathways are already in use in the clinics, and still more are being tested in preclinical models and clinical trials. Discussed here are the chemical and pharmacological properties that present challenges for the translation of these potentially toxic molecules.
Related Concept Videos
Translational Regulation
Gas Exchange and Transport
Cotranslational Protein Translocation
Sec61 channel partners for cotranslational translocation
During cotranslational translocation, the Sec61 channel partners with the signal recognition particle (SRP), the signal recognition particle receptor (SR), and the ribosomes to transport the nascent polypeptide chain...
Microorganisms in Medicine and Therapeutics
Leaky Scanning
Improving Translational Accuracy

