Related Experiment Video
Updated: Jun 6, 2026
11:17
Thoracoscopic Extended Right Middle Plus Lower Sleeve Lobectomy for Non-Small-Cell Lung Cancer
Published on: February 27, 2026
Adult Wilms tumour
Romuald Zdrojowy1, Krystyna Sawicz-Birkowska, Wojciech Apoznański
1Department of Urology and Urological Oncology, University of Medicine, Borowska Str. 213, 50-556 Wrocław, Poland. zdrojowy@urol.am.wroc.pl
International Urology and Nephrology
|November 27, 2010
Summary
Adult Wilms tumour is rare and aggressive. Patients over 16 experienced poorer prognoses and ineffective second-line therapies, indicating a need for new treatment strategies for this rare cancer.
Area of Science:
- Oncology
- Paediatric Oncology
- Urology
Background:
- Wilms tumour is the predominant renal malignancy in children, rare in adults.
- This study focuses on 9 adult patients diagnosed with Wilms tumour.
Purpose of the Study:
- To present the clinical presentation, staging, histology, treatment, and prognosis of adult Wilms tumour patients.
- To highlight the challenges and outcomes associated with treating Wilms tumour in an adult population.
Main Methods:
- Retrospective review of 9 adult patients (17-32 years old) with Wilms tumour.
- Tumour staging according to the International Society of Paediatric Oncology (SIOP) classification.
- Treatment included the SIOP 93-01 paediatric protocol for some patients, involving preoperative chemotherapy (VCR + ACT D).
Main Results:
- Complete remission achieved in 3 patients.
- 3 patients relapsed between 6-30 months post-remission.
- Second-line therapy was ineffective in relapsed cases and those treated initially elsewhere.
Conclusions:
- Adult Wilms tumour cases exhibit more aggressive histology.
- Adult patients with Wilms tumour have a poorer prognosis compared to paediatric cases.
