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A bipotent mesoderm subset identified via colony-forming assay

Mervin C Yoder1

  • 1Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, 46202, USA. myoder@iupui.edu

Cell Stem Cell
|November 30, 2010
PubMed
Summary

No abstract available in PubMed .

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Production of Formed Elements01:34

Production of Formed Elements

Hemangioblasts are multipotent stem cells originating from the mesoderm. They give rise to hematopoietic stem cells (HSCs), which undergo hematopoiesis to produce all the formed elements of blood. This process is regulated by a complex network of hematopoietic growth factors, including transcription factors, growth factors, and cytokines. These factors stimulate the HSCs to divide and differentiate, though some HSCs remain undifferentiated to maintain a self-renewing pool.
Most HSCs commit to...

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