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[Intestinal microflora of autistic children]
Alicja Ekiel1, Malgorzata Aptekorz, Beata Kazek
1Katedra i Zakład Mikrobiologii Lekarskiej, Uniwersytetu Medycznego.
Medycyna Doswiadczalna I Mikrobiologia
|December 1, 2010
Summary
Gastrointestinal issues are common in autistic children, often linked to gut bacteria imbalances. This study found significant differences in intestinal microflora between autistic and healthy children, suggesting a potential therapeutic target.
Area of Science:
- Microbiology
- Neurodevelopmental Disorders
- Gastroenterology
Background:
- Autistic behavior is frequently associated with gastrointestinal disturbances like pain, constipation, and diarrhea.
- These symptoms are often linked to disruptions in the normal balance of intestinal microflora.
Purpose of the Study:
- To investigate and identify differences in the intestinal microflora composition between children with autism and healthy controls.
- To explore the potential role of specific microbial strains in the etiology of autistic disorders.
Main Methods:
- Stool samples were collected from both autistic and healthy children.
- Microbial analysis focused on the isolation and identification of bacterial strains, including Clostridium spp., enterococci, lactobacilli, staphylococci, and Candida spp.
Main Results:
- Strains of Clostridium spp. and enterococci were found more frequently in the stool samples of autistic children.
- Lactobacilli were isolated less frequently from autistic children compared to healthy controls.
- Quantitative differences were noted in staphylococci, Candida spp., and Clostridium perfringens between the two groups.
Conclusions:
- Significant differences exist in the intestinal microflora of autistic children compared to healthy children.
- Monitoring and stabilizing intestinal microflora may offer therapeutic benefits for individuals with autism.
- Understanding the role of specific microbial strains in autism etiology is crucial for developing targeted therapies.
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